 Genetic Vectors
"Genetic Vectors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.
| Descriptor ID |
D005822
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| MeSH Number(s) |
G05.360.337
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| Concept/Terms |
Genetic Vectors- Genetic Vectors
- Genetic Vector
- Vector, Genetic
- Vectors, Genetic
Shuttle Vectors- Shuttle Vectors
- Shuttle Vector
- Vector, Shuttle
- Vectors, Shuttle
Cloning Vectors- Cloning Vectors
- Cloning Vector
- Vector, Cloning
- Vectors, Cloning
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Below are MeSH descriptors whose meaning is more general than "Genetic Vectors".
Below are MeSH descriptors whose meaning is more specific than "Genetic Vectors".
This graph shows the total number of publications written about "Genetic Vectors" by people in this website by year, and whether "Genetic Vectors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 1 | 2 | 3 | | 1988 | 1 | 1 | 2 | | 1989 | 0 | 4 | 4 | | 1990 | 0 | 3 | 3 | | 1991 | 0 | 2 | 2 | | 1992 | 2 | 6 | 8 | | 1993 | 0 | 6 | 6 | | 1994 | 2 | 0 | 2 | | 1995 | 6 | 3 | 9 | | 1996 | 6 | 4 | 10 | | 1997 | 3 | 6 | 9 | | 1998 | 6 | 7 | 13 | | 1999 | 6 | 4 | 10 | | 2000 | 6 | 6 | 12 | | 2001 | 10 | 5 | 15 | | 2002 | 12 | 19 | 31 | | 2003 | 9 | 16 | 25 | | 2004 | 9 | 6 | 15 | | 2005 | 9 | 15 | 24 | | 2006 | 3 | 5 | 8 | | 2007 | 11 | 10 | 21 | | 2008 | 15 | 7 | 22 | | 2009 | 7 | 10 | 17 | | 2010 | 7 | 7 | 14 | | 2011 | 6 | 12 | 18 | | 2012 | 5 | 6 | 11 | | 2013 | 12 | 13 | 25 | | 2014 | 1 | 9 | 10 | | 2015 | 6 | 13 | 19 | | 2016 | 3 | 4 | 7 | | 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Genetic Vectors" by people in Profiles.
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Gernoux G, Wilson JM, Mueller C. Regulatory and Exhausted T Cell Responses to AAV Capsid. Hum Gene Ther. 2017 Apr; 28(4):338-349.
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Gray-Edwards HL, Regier DS, Shirley JL, Randle AN, Salibi N, Thomas SE, Latour YL, Johnston J, Golas G, Maguire AS, Taylor AR, Sorjonen DC, McCurdy VJ, Christopherson PW, Bradbury AM, Beyers RJ, Johnson AK, Brunson BL, Cox NR, Baker HJ, Denney TS, Sena-Esteves M, Tifft CJ, Martin DR. Novel Biomarkers of Human GM1 Gangliosidosis Reflect the Clinical Efficacy of Gene Therapy in a Feline Model. Mol Ther. 2017 04 05; 25(4):892-903.
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Bradbury AM, Peterson TA, Gross AL, Wells SZ, McCurdy VJ, Wolfe KG, Dennis JC, Brunson BL, Gray-Edwards H, Randle AN, Johnson AK, Morrison EE, Cox NR, Baker HJ, Sena-Esteves M, Martin DR. AAV-mediated gene delivery attenuates neuroinflammation in feline Sandhoff disease. Neuroscience. 2017 Jan 06; 340:117-125.
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Gruenert AK, Czugala M, Mueller C, Schmeer M, Schleef M, Kruse FE, Fuchsluger TA. Self-Complementary Adeno-Associated Virus Vectors Improve Transduction Efficiency of Corneal Endothelial Cells. PLoS One. 2016; 11(3):e0152589.
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Stoica L, Todeasa SH, Cabrera GT, Salameh JS, ElMallah MK, Mueller C, Brown RH, Sena-Esteves M. Adeno-associated virus-delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model. Ann Neurol. 2016 Apr; 79(4):687-700.
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Loring HS, ElMallah MK, Flotte TR. Development of rAAV2-CFTR: History of the First rAAV Vector Product to be Used in Humans. Hum Gene Ther Methods. 2016 Apr; 27(2):49-58.
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Yin H, Song CQ, Dorkin JR, Zhu LJ, Li Y, Wu Q, Park A, Yang J, Suresh S, Bizhanova A, Gupta A, Bolukbasi MF, Walsh S, Bogorad RL, Gao G, Weng Z, Dong Y, Koteliansky V, Wolfe SA, Langer R, Xue W, Anderson DG. Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo. Nat Biotechnol. 2016 Mar; 34(3):328-33.
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Toro Cabrera G, Mueller C. Design of shRNA and miRNA for Delivery to the CNS. Methods Mol Biol. 2016; 1382:67-80.
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Schnepp BC, Chulay JD, Ye GJ, Flotte TR, Trapnell BC, Johnson PR. Recombinant Adeno-Associated Virus Vector Genomes Take the Form of Long-Lived, Transcriptionally Competent Episomes in Human Muscle. Hum Gene Ther. 2016 Jan; 27(1):32-42.
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Choudhury SR, Harris AF, Cabral DJ, Keeler AM, Sapp E, Ferreira JS, Gray-Edwards HL, Johnson JA, Johnson AK, Su Q, Stoica L, DiFiglia M, Aronin N, Martin DR, Gao G, Sena-Esteves M. Widespread Central Nervous System Gene Transfer and Silencing After Systemic Delivery of Novel AAV-AS Vector. Mol Ther. 2016 Apr; 24(4):726-35.
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