"Genetic Vectors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.
| Descriptor ID |
D005822
|
| MeSH Number(s) |
G05.360.337
|
| Concept/Terms |
Genetic Vectors- Genetic Vectors
- Genetic Vector
- Vector, Genetic
- Vectors, Genetic
Shuttle Vectors- Shuttle Vectors
- Shuttle Vector
- Vector, Shuttle
- Vectors, Shuttle
Cloning Vectors- Cloning Vectors
- Cloning Vector
- Vector, Cloning
- Vectors, Cloning
|
Below are MeSH descriptors whose meaning is more general than "Genetic Vectors".
Below are MeSH descriptors whose meaning is more specific than "Genetic Vectors".
This graph shows the total number of publications written about "Genetic Vectors" by people in this website by year, and whether "Genetic Vectors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 7 | 7 |
| 1994 | 2 | 0 | 2 |
| 1995 | 6 | 4 | 10 |
| 1996 | 5 | 3 | 8 |
| 1997 | 4 | 6 | 10 |
| 1998 | 4 | 7 | 11 |
| 1999 | 4 | 3 | 7 |
| 2000 | 5 | 5 | 10 |
| 2001 | 6 | 4 | 10 |
| 2002 | 8 | 13 | 21 |
| 2003 | 8 | 16 | 24 |
| 2004 | 9 | 5 | 14 |
| 2005 | 8 | 15 | 23 |
| 2006 | 3 | 5 | 8 |
| 2007 | 12 | 10 | 22 |
| 2008 | 14 | 9 | 23 |
| 2009 | 7 | 11 | 18 |
| 2010 | 7 | 11 | 18 |
| 2011 | 6 | 9 | 15 |
| 2012 | 5 | 6 | 11 |
| 2013 | 12 | 12 | 24 |
| 2014 | 2 | 13 | 15 |
| 2015 | 7 | 12 | 19 |
| 2016 | 4 | 11 | 15 |
| 2017 | 12 | 16 | 28 |
| 2018 | 6 | 14 | 20 |
| 2019 | 9 | 7 | 16 |
| 2020 | 8 | 5 | 13 |
| 2021 | 10 | 6 | 16 |
| 2022 | 5 | 5 | 10 |
| 2023 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Genetic Vectors" by people in Profiles.
-
Chan YK, Flotte TR. Analyzing clinical observations to better understand and manage immune responses to AAV gene therapies. Mol Ther. 2023 04 05; 31(4):913-914.
-
Arjomandnejad M, Dasgupta I, Flotte TR, Keeler AM. Immunogenicity of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Transfer. BioDrugs. 2023 May; 37(3):311-329.
-
Namkung S, Tran NT, Manokaran S, He R, Su Q, Xie J, Gao G, Tai PWL. Direct ITR-to-ITR Nanopore Sequencing of AAV Vector Genomes. Hum Gene Ther. 2022 11; 33(21-22):1187-1196.
-
Gonzalez TJ, Simon KE, Blondel LO, Fanous MM, Roger AL, Maysonet MS, Devlin GW, Smith TJ, Oh DK, Havlik LP, Castellanos Rivera RM, Piedrahita JA, ElMallah MK, Gersbach CA, Asokan A. Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing. Nat Commun. 2022 10 10; 13(1):5947.
-
McElroy A, Sena-Esteves M, Arjomandnejad M, Keeler AM, Gray-Edwards HL. Redosing Adeno-Associated Virus Gene Therapy to the Central Nervous System. Hum Gene Ther. 2022 09; 33(17-18):889-892.
-
Tran NT, Lecomte E, Saleun S, Namkung S, Robin C, Weber K, Devine E, Blouin V, Adjali O, Ayuso E, Gao G, Penaud-Budloo M, Tai PWL. Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity. Hum Gene Ther. 2022 04; 33(7-8):371-388.
-
Wang J, Zhang Y, Mendonca CA, Yukselen O, Muneeruddin K, Ren L, Liang J, Zhou C, Xie J, Li J, Jiang Z, Kucukural A, Shaffer SA, Gao G, Wang D. AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice. Nature. 2022 04; 604(7905):343-348.
-
Muhuri M, Levy DI, Schulz M, McCarty D, Gao G. Durability of transgene expression after rAAV gene therapy. Mol Ther. 2022 04 06; 30(4):1364-1380.
-
Arjomandnejad M, Keeler AM. Evaluating Readministration of Adeno-Associated Virus for Gene Therapy. Hum Gene Ther. 2022 03; 33(5-6):218-220.
-
Flotte TR, Gessler DJ. Gene Therapy for Rare Neurological Disorders. Clin Pharmacol Ther. 2022 04; 111(4):743-757.