"Receptor, Notch3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
| Descriptor ID |
D000071656
|
| MeSH Number(s) |
D12.776.543.750.725.875 D12.776.930.770.875
|
| Concept/Terms |
Receptor, Notch3- Receptor, Notch3
- Notch-3 Protein
- Notch 3 Protein
- Notch3 Protein
- Notch-3 Receptor
- Notch 3 Receptor
- Notch3 Receptor
- Neurogenic Locus Notch Homolog Protein 3
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch3".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch3".
This graph shows the total number of publications written about "Receptor, Notch3" by people in this website by year, and whether "Receptor, Notch3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Notch3" by people in Profiles.
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Riordan CP, Lyon HN, McIntyre JK. Craniosynostosis of the Metopic Suture in a Patient With CADASIL/Lehman Syndrome. J Craniofac Surg. 2021 Nov-Dec 01; 32(8):e737-e739.
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Edwards AK, Glithero K, Grzesik P, Kitajewski AA, Munabi NC, Hardy K, Tan QK, Schonning M, Kangsamaksin T, Kitajewski JK, Shawber CJ, Wu JK. NOTCH3 regulates stem-to-mural cell differentiation in infantile hemangioma. JCI Insight. 2017 11 02; 2(21).
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Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV. Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development. 2015 Jan 15; 142(2):258-67.
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Vernon HJ, Bytyci Telegrafi A, Batista D, Owegi M, Leigh R. 6p25 microdeletion: white matter abnormalities in an adult patient. Am J Med Genet A. 2013 Jul; 161A(7):1686-9.
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Cui H, Kong Y, Xu M, Zhang H. Notch3 functions as a tumor suppressor by controlling cellular senescence. Cancer Res. 2013 Jun 01; 73(11):3451-9.
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Indraccolo S, Minuzzo S, Masiero M, Pusceddu I, Persano L, Moserle L, Reboldi A, Favaro E, Mecarozzi M, Di Mario G, Screpanti I, Ponzoni M, Doglioni C, Amadori A. Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy. Cancer Res. 2009 Feb 15; 69(4):1314-23.
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Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases. Blood. 2009 Feb 19; 113(8):1689-98.