Minichromosome Maintenance Proteins
"Minichromosome Maintenance Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that were originally identified in SACCHAROMYCES CEREVISIAE as being essential for maintaining the structure of minichromosomes00. They form into a protein complex that has helicase activity and is involved in a variety of DNA-related functions including replication elongation, RNA transcription, chromatin remodeling, and genome stability.
| Descriptor ID |
D064110
|
| MeSH Number(s) |
D08.811.277.040.025.159.186 D08.811.399.340.186 D12.776.167.409 D12.776.660.235.500 D12.776.664.235.750
|
| Concept/Terms |
MCM Protein Complex- MCM Protein Complex
- MCM2-7 Helicase
- Helicase, MCM2-7
- MCM2 7 Helicase
- MCM2-7 Complex
- MCM2 7 Complex
|
Below are MeSH descriptors whose meaning is more general than "Minichromosome Maintenance Proteins".
Below are MeSH descriptors whose meaning is more specific than "Minichromosome Maintenance Proteins".
This graph shows the total number of publications written about "Minichromosome Maintenance Proteins" by people in this website by year, and whether "Minichromosome Maintenance Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Minichromosome Maintenance Proteins" by people in Profiles.
-
Dukaj L, Rhind N. The capacity of origins to load MCM establishes replication timing patterns. PLoS Genet. 2021 03; 17(3):e1009467.
-
Dondik Y, Lei Z, Gaskins J, Pagidas K. Minichromosome maintenance complex component 8 and 9 gene expression in the menstrual cycle and unexplained primary ovarian insufficiency. J Assist Reprod Genet. 2019 Jan; 36(1):57-64.
-
Das SP, Rhind N. How and why multiple MCMs are loaded at origins of DNA replication. Bioessays. 2016 07; 38(7):613-7.
-
Das SP, Borrman T, Liu VW, Yang SC, Bechhoefer J, Rhind N. Replication timing is regulated by the number of MCMs loaded at origins. Genome Res. 2015 Dec; 25(12):1886-92.
-
Hanly TJ, Henson MA. Dynamic model-based analysis of furfural and HMF detoxification by pure and mixed batch cultures of S. cerevisiae and S. stipitis. Biotechnol Bioeng. 2014 Feb; 111(2):272-84.