Aromatase Inhibitors

"Aromatase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds that inhibit AROMATASE in order to reduce production of estrogenic steroid hormones.

Descriptor ID	D047072
MeSH Number(s)	D27.505.519.389.870.300 D27.505.696.399.450.327.149 D27.505.696.399.450.855.300
Concept/Terms	Aromatase Inhibitors Aromatase Inhibitors Inhibitors, Aromatase

Below are MeSH descriptors whose meaning is more general than "Aromatase Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Steroid Synthesis Inhibitors [D27.505.519.389.870]
Aromatase Inhibitors [D27.505.519.389.870.300]
Physiological Effects of Drugs [D27.505.696]
Hormones, Hormone Substitutes, and Hormone Antagonists [D27.505.696.399]
Hormone Antagonists [D27.505.696.399.450]
Estrogen Antagonists [D27.505.696.399.450.327]
Aromatase Inhibitors [D27.505.696.399.450.327.149]
Steroid Synthesis Inhibitors [D27.505.696.399.450.855]
Aromatase Inhibitors [D27.505.696.399.450.855.300]

Below are MeSH descriptors whose meaning is related to "Aromatase Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Aromatase Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Aromatase Inhibitors" by people in this website by year, and whether "Aromatase Inhibitors" was a major or minor topic of these publications.

Bar chart showing 24 publications over 14 distinct years, with a maximum of 3 publications in 2011 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	1	0	1
2008	1	0	1
2009	1	1	2
2010	2	0	2
2011	1	2	3
2012	1	1	2
2013	1	1	2
2016	0	1	1
2017	1	0	1
2018	0	2	2
2019	3	0	3
2021	2	0	2
2022	1	0	1
2023	0	1	1

Below are the most recent publications written about "Aromatase Inhibitors" by people in Profiles.

Schwartz GN, Kaufman PA, Giridhar KV, Marotti JD, Chamberlin MD, Arrick BA, Makari-Judson G, Goetz MP, Soucy SM, Kolling F, Demidenko E, Miller TW. Alternating 17?-Estradiol and Aromatase Inhibitor Therapies Is Efficacious in Postmenopausal Women with Advanced Endocrine-Resistant ER+ Breast Cancer. Clin Cancer Res. 2023 08 01; 29(15):2767-2773.

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Singh Y, Jaswal S, Singh S, Verma SK, Thareja S. Dual aromatase-steroid sulfatase inhibitors (DASI's) for the treatment of breast cancer: a structure guided ligand based designing approach. J Biomol Struct Dyn. 2023 12; 41(20):10604-10626.

View in: PubMed
Banjare L, Singh Y, Verma SK, Singh AK, Kumar P, Kumar S, Jain AK, Thareja S. Multifaceted 3D-QSAR analysis for the identification of pharmacophoric features of biphenyl analogues as aromatase inhibitors. J Biomol Struct Dyn. 2023 03; 41(4):1322-1341.

View in: PubMed
Mishra K, Verma SK, Ratre P, Banjare L, Jain A, Thareja S, Jain AK. In Silico Molecular Interaction Studies of Chitosan Polymer with Aromatase Inhibitor: Leads to Letrozole Nanoparticles for the Treatment of Breast Cancer. Anticancer Agents Med Chem. 2021; 21(9):1191-1199.

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Owens DK, Davidson KW, Krist AH, Barry MJ, Cabana M, Caughey AB, Doubeni CA, Epling JW, Kubik M, Landefeld CS, Mangione CM, Pbert L, Silverstein M, Tseng CW, Wong JB. Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2019 09 03; 322(9):857-867.

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Richards R, Keating E, Boucher JE. Targeted Therapies: Treatment Options for Patients With Metastatic Breast Cancer. Clin J Oncol Nurs. 2019 08 01; 23(4):434-438.

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Bird ST, Toh S, Sahin L, Andrade SE, Gelperin K, Taylor L, Song J, Hampp C. Misclassification in Assessment of First Trimester In-utero Exposure to Drugs Used Proximally to Conception: the Example of Letrozole Utilization for Infertility Treatment. Am J Epidemiol. 2019 02 01; 188(2):418-425.

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Zhang M, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D. Synthesis and Structure-Activity Relationships of Tetrahydro-?-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents. Anticancer Res. 2018 Aug; 38(8):4425-4433.

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Carrasquillo R, Chu K, Ramasamy R. Novel Therapy for Male Hypogonadism. Curr Urol Rep. 2018 Jun 09; 19(8):63.

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Prior AM, Yu X, Park EJ, Kondratyuk TP, Lin Y, Pezzuto JM, Sun D. Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1. Bioorg Med Chem Lett. 2017 12 15; 27(24):5393-5399.

View in: PubMed

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