Interferon Regulatory Factor-2
"Interferon Regulatory Factor-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that represses transcription of TYPE I INTERFERONS and activates transcription of HISTONE H4.
| Descriptor ID |
D050836
|
| MeSH Number(s) |
D12.644.360.024.302.249 D12.776.157.057.050.249 D12.776.260.504.249 D12.776.476.024.385.249 D12.776.930.332.249
|
| Concept/Terms |
Interferon Regulatory Factor-2- Interferon Regulatory Factor-2
- Interferon Regulatory Factor 2
- HINF-M Transcription Factor
- HINF M Transcription Factor
- Transcription Factor, HINF-M
- IRF-2 Transcription Factor
- IRF 2 Transcription Factor
- Transcription Factor, IRF-2
- Histone Nuclear Factor M
|
Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-2".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-2".
This graph shows the total number of publications written about "Interferon Regulatory Factor-2" by people in this website by year, and whether "Interferon Regulatory Factor-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Interferon Regulatory Factor-2" by people in Profiles.
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Sari G, Dhatchinamoorthy K, Orellano-Ariza L, Ferreira LM, Brehm MA, Rock K. IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas. J Exp Clin Cancer Res. 2024 Oct 02; 43(1):276.
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Kriegsman BA, Vangala P, Chen BJ, Meraner P, Brass AL, Garber M, Rock KL. Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression. J Immunol. 2019 10 01; 203(7):1999-2010.
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Xie RL, van Wijnen AJ, van der Meijden CM, Stein JL, Stein GS. Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells. Cancer Res. 2002 May 01; 62(9):2510-5.
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Aziz F, van Wijnen AJ, Vaughan PS, Wu S, Shakoori AR, Lian JB, Soprano KJ, Stein JL, Stein GS. The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes. Mol Biol Rep. 1998 Jan; 25(1):1-12.
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Birnbaum MJ, van Zundert B, Vaughan PS, Whitmarsh AJ, van Wijnen AJ, Davis RJ, Stein GS, Stein JL. Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo. J Cell Biochem. 1997 Aug 01; 66(2):175-83.