Deoxyribonucleases, Type II Site-Specific
"Deoxyribonucleases, Type II Site-Specific" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.
| Descriptor ID |
D015252
|
| MeSH Number(s) |
D08.811.150.280.260 D08.811.277.352.335.350.300.260 D08.811.277.352.355.325.300.260
|
| Concept/Terms |
Deoxyribonucleases, Type II Site-Specific- Deoxyribonucleases, Type II Site-Specific
- Deoxyribonucleases, Type II Site Specific
- Deoxyribonucleases, Type II, Site Specific
- Deoxyribonucleases, Type II, Site-Specific
- Type II Site Specific Deoxyribonucleases
- Type II Site-Specific Deoxyribonucleases
- Restriction Endonucleases, Type II
- DNase, Site Specific, Type II
- Site-Specific DNase, Type II
- Site Specific DNase, Type II
- Type II Site Specific DNase
- Type II Site-Specific DNase
- DNase, Site-Specific, Type II
- Type II Restriction Enzymes
- DNA Restriction Enzymes, Type II
|
Below are MeSH descriptors whose meaning is more general than "Deoxyribonucleases, Type II Site-Specific".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonucleases, Type II Site-Specific".
This graph shows the total number of publications written about "Deoxyribonucleases, Type II Site-Specific" by people in this website by year, and whether "Deoxyribonucleases, Type II Site-Specific" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxyribonucleases, Type II Site-Specific" by people in Profiles.
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Belaghzal H, Dekker J, Gibcus JH. Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation. Methods. 2017 07 01; 123:56-65.
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Golovenko D, Manakova E, Zakrys L, Zaremba M, Sasnauskas G, Gra?ulis S, Siksnys V. Structural insight into the specificity of the B3 DNA-binding domains provided by the co-crystal structure of the C-terminal fragment of BfiI restriction enzyme. Nucleic Acids Res. 2014 Apr; 42(6):4113-22.
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Zhu C, Gupta A, Hall VL, Rayla AL, Christensen RG, Dake B, Lakshmanan A, Kuperwasser C, Stormo GD, Wolfe SA. Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases. Nucleic Acids Res. 2013 Feb 01; 41(4):2455-65.
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Manakova E, Grazulis S, Zaremba M, Tamulaitiene G, Golovenko D, Siksnys V. Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease. Nucleic Acids Res. 2012 Aug; 40(14):6741-51.
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Andersen SL, Kuo HK, Savukoski D, Brodsky MH, Sekelsky J. Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila. PLoS Genet. 2011 Oct; 7(10):e1002315.
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Zhu C, Smith T, McNulty J, Rayla AL, Lakshmanan A, Siekmann AF, Buffardi M, Meng X, Shin J, Padmanabhan A, Cifuentes D, Giraldez AJ, Look AT, Epstein JA, Lawson ND, Wolfe SA. Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish. Development. 2011 Oct; 138(20):4555-64.
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Windbichler N, Menichelli M, Papathanos PA, Thyme SB, Li H, Ulge UY, Hovde BT, Baker D, Monnat RJ, Burt A, Crisanti A. A synthetic homing endonuclease-based gene drive system in the human malaria mosquito. Nature. 2011 May 12; 473(7346):212-5.
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Sharma V, Fretwell D, Crees Z, Kerege A, Klopper JP. Thyroid cancer resistance to vitamin D receptor activation is associated with 24-hydroxylase levels but not the ff FokI polymorphism. Thyroid. 2010 Oct; 20(10):1103-11.
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Gupta A, Meng X, Zhu LJ, Lawson ND, Wolfe SA. Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases. Nucleic Acids Res. 2011 Jan; 39(1):381-92.
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Keum JW, Bermudez H. Enhanced resistance of DNA nanostructures to enzymatic digestion. Chem Commun (Camb). 2009 Dec 07; (45):7036-8.