 Mitogen-Activated Protein Kinase 9
"Mitogen-Activated Protein Kinase 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 48 and 54 KD exist due to multiple ALTERNATIVE SPLICING.
| Descriptor ID |
D048056
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| MeSH Number(s) |
D08.811.913.696.620.682.700.567.513.750 D08.811.913.696.620.682.700.646.750.374.750 D12.644.360.450.340.750 D12.776.476.450.340.750
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| Concept/Terms |
Mitogen-Activated Protein Kinase 9- Mitogen-Activated Protein Kinase 9
- Mitogen Activated Protein Kinase 9
- c-jun N-terminal Kinase 2
- c jun N terminal Kinase 2
- JNK2 Kinase
- MAPK9 Mitogen-Activated Protein Kinase
- MAPK9 Mitogen Activated Protein Kinase
- Stress-Activated Protein Kinase JNK2
- Stress Activated Protein Kinase JNK2
- c-jun Kinase-2
- Kinase-2, c-jun
- c jun Kinase 2
- JNK2 Stress-Activated Protein Kinase
- JNK2 Stress Activated Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 9".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 9".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 9" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 1 | 1 | | 2002 | 0 | 4 | 4 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 3 | 0 | 3 | | 2011 | 1 | 1 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 9" by people in Profiles.
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Liu J, Wang T, Creighton CJ, Wu SP, Ray M, Janardhan KS, Willson CJ, Cho SN, Castro PD, Ittmann MM, Li JL, Davis RJ, DeMayo FJ. JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression. Nat Commun. 2019 05 14; 10(1):2148.
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Cubero FJ, Zoubek ME, Hu W, Peng J, Zhao G, Nevzorova YA, Al Masaoudi M, Bechmann LP, Boekschoten MV, Muller M, Preisinger C, Gassler N, Canbay AE, Luedde T, Davis RJ, Liedtke C, Trautwein C. Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury. Gastroenterology. 2016 Apr; 150(4):968-81.
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Nisticò R, Florenzano F, Mango D, Ferraina C, Grilli M, Di Prisco S, Nobili A, Saccucci S, D'Amelio M, Morbin M, Marchi M, Mercuri NB, Davis RJ, Pittaluga A, Feligioni M. Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release. Sci Rep. 2015; 5:9035.
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You H, Padmashali RM, Ranganathan A, Lei P, Girnius N, Davis RJ, Andreadis ST. JNK regulates compliance-induced adherens junctions formation in epithelial cells and tissues. J Cell Sci. 2013 Jun 15; 126(Pt 12):2718-29.
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Han MS, Jung DY, Morel C, Lakhani SA, Kim JK, Flavell RA, Davis RJ. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science. 2013 Jan 11; 339(6116):218-22.
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Cellurale C, Girnius N, Jiang F, Cavanagh-Kyros J, Lu S, Garlick DS, Mercurio AM, Davis RJ. Role of JNK in mammary gland development and breast cancer. Cancer Res. 2012 Jan 15; 72(2):472-81.
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Das M, Garlick DS, Greiner DL, Davis RJ. The role of JNK in the development of hepatocellular carcinoma. Genes Dev. 2011 Mar 15; 25(6):634-45.
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Sherrin T, Blank T, Hippel C, Rayner M, Davis RJ, Todorovic C. Hippocampal c-Jun-N-terminal kinases serve as negative regulators of associative learning. J Neurosci. 2010 Oct 6; 30(40):13348-61.
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Cellurale C, Weston CR, Reilly J, Garlick DS, Jerry DJ, Sluss HK, Davis RJ. Role of JNK in a Trp53-dependent mouse model of breast cancer. PLoS One. 2010 Aug 30; 5(8):e12469.
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Barnat M, Enslen H, Propst F, Davis RJ, Soares S, Nothias F. Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration. J Neurosci. 2010 Jun 9; 30(23):7804-16.
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