Activating Transcription Factors
"Activating Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact with early promoters from ADENOVIRUSES. They are a family of basic leucine zipper transcription factors that bind to the consensus site TGACGTCA of the cyclic AMP response element, and are closely related to CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN.
Descriptor ID |
D051696
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MeSH Number(s) |
D12.776.260.108.061 D12.776.930.127.061
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Activating Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Activating Transcription Factors".
This graph shows the total number of publications written about "Activating Transcription Factors" by people in this website by year, and whether "Activating Transcription Factors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2011 | 1 | 1 | 2 |
2012 | 2 | 0 | 2 |
2016 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Activating Transcription Factors" by people in Profiles.
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Wang YT, Lim Y, McCall MN, Huang KT, Haynes CM, Nehrke K, Brookes PS. Cardioprotection by the mitochondrial unfolded protein response requires ATF5. Am J Physiol Heart Circ Physiol. 2019 08 01; 317(2):H472-H478.
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Deng P, Haynes CM. Mitochondrial dysfunction in cancer: Potential roles of ATF5 and the mitochondrial UPR. Semin Cancer Biol. 2017 12; 47:43-49.
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Juliana CA, Yang J, Rozo AV, Good A, Groff DN, Wang SZ, Green MR, Stoffers DA. ATF5 regulates ?-cell survival during stress. Proc Natl Acad Sci U S A. 2017 02 07; 114(6):1341-1346.
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Fiorese CJ, Schulz AM, Lin YF, Rosin N, Pellegrino MW, Haynes CM. The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR. Curr Biol. 2016 08 08; 26(15):2037-2043.
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Sheng Z, Murphy SF, Guo S, Green MR. A diphtheria toxin negative selection in RNA interference screening. Methods Mol Biol. 2014; 1176:59-72.
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Wang SZ, Ou J, Zhu LJ, Green MR. Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):18589-94.
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Pukkila-Worley R, Feinbaum R, Kirienko NV, Larkins-Ford J, Conery AL, Ausubel FM. Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection. PLoS Genet. 2012; 8(6):e1002733.
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Patel N, Klassert TE, Greco SJ, Patel SA, Munoz JL, Reddy BY, Bryan M, Campbell N, Kokorina N, Sabaawy HE, Rameshwar P. Developmental regulation of TAC1 in peptidergic-induced human mesenchymal stem cells: implication for spinal cord injury in zebrafish. Stem Cells Dev. 2012 Jan 20; 21(2):308-20.
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Sheng Z, Ma L, Sun JE, Zhu LJ, Green MR. BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription. Blood. 2011 Sep 08; 118(10):2840-8.
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Wang X, Gulhati P, Li J, Dobner PR, Weiss H, Townsend CM, Evers BM. Characterization of promoter elements regulating the expression of the human neurotensin/neuromedin N gene. J Biol Chem. 2011 Jan 07; 286(1):542-54.