A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.

Descriptor ID	D034702
MeSH Number(s)	D12.776.157.725.813.750.905 D12.776.624.664.700.915 D12.776.664.962.813.750.902
Concept/Terms	RNA-Binding Protein FUS RNA-Binding Protein FUS RNA Binding Protein FUS TLS Protein POMp75 Protein Translocated in Liposarcoma Protein FUS RNA-Binding Protein FUS RNA Binding Protein RNA-Binding Protein, FUS Fusion Protein in Myxoid Liposarcoma FUS Protein hnRNP P2

Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein FUS".

Below are MeSH descriptors whose meaning is related to "RNA-Binding Protein FUS".

Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein FUS".