Major Histocompatibility Complex

"Major Histocompatibility Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) TRANSPLANTATION ANTIGENS, genes which control the structure of the IMMUNE RESPONSE-ASSOCIATED ANTIGENS, HUMAN; the IMMUNE RESPONSE GENES which control the ability of an animal to respond immunologically to antigenic stimuli, and genes which determine the structure and/or level of the first four components of complement.

Descriptor ID	D008285
MeSH Number(s)	G05.360.340.024.340.610 G05.360.340.024.380.500 G12.500.500
Concept/Terms	Major Histocompatibility Complex Major Histocompatibility Complex Complex, Major Histocompatibility Complices, Major Histocompatibility Histocompatibility Complex, Major Histocompatibility Complices, Major Major Histocompatibility Complices Histocompatibility Complex Complex, Histocompatibility Complices, Histocompatibility Histocompatibility Complices

Below are MeSH descriptors whose meaning is more general than "Major Histocompatibility Complex".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Major Histocompatibility Complex [G05.360.340.024.340.610]
Genetic Loci [G05.360.340.024.380]
Major Histocompatibility Complex [G05.360.340.024.380.500]
Immune System Phenomena [G12]
Immunogenetic Phenomena [G12.500]
Major Histocompatibility Complex [G12.500.500]

Below are MeSH descriptors whose meaning is related to "Major Histocompatibility Complex".

Below are MeSH descriptors whose meaning is more specific than "Major Histocompatibility Complex".

Major Histocompatibility Complex
Genes, MHC Class I
Genes, MHC Class II

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Major Histocompatibility Complex" by people in this website by year, and whether "Major Histocompatibility Complex" was a major or minor topic of these publications.

Bar chart showing 51 publications over 24 distinct years, with a maximum of 6 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1997	1	0	1
1998	1	1	2
1999	2	3	5
2000	0	3	3
2001	1	0	1
2003	1	2	3
2004	2	0	2
2005	2	0	2
2006	3	2	5
2007	2	1	3
2008	1	0	1
2009	4	2	6
2010	1	0	1
2011	0	2	2
2012	1	0	1
2014	1	1	2
2015	1	0	1
2017	0	2	2
2019	1	1	2
2020	1	0	1
2022	0	1	1
2023	0	1	1
2024	0	2	2

Below are the most recent publications written about "Major Histocompatibility Complex" by people in Profiles.

Darguzyte M, Antczak P, Bachurski D, Hoelker P, Abedpour N, Gholamipoorfard R, Schl??er HA, Wennhold K, Thelen M, Garcia-Marquez MA, Koenig J, Schneider A, Braun T, Klawonn F, Damrat M, Rahman M, Kleid JM, Theobald SJ, Bauer E, von Kaisenberg C, Talbot SR, Shultz LD, Soper B, Stripecke R. Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles. Cells. 2024 Oct 12; 13(20).

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Lo WL, Huseby ES. The partitioning of TCR repertoires by thymic selection. J Exp Med. 2024 Oct 07; 221(10).

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Cruz FM, Chan A, Rock KL. Pathways of MHC I cross-presentation of exogenous antigens. Semin Immunol. 2023 03; 66:101729.

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Huseby ES, Teixeiro E. The perception and response of T cells to a changing environment are based on the law of initial value. Sci Signal. 2022 05 31; 15(736):eabj9842.

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Gil A, Kamga L, Chirravuri-Venkata R, Aslan N, Clark F, Ghersi D, Luzuriaga K, Selin LK. Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor a and ? Repertoires. mBio. 2020 03 17; 11(2).

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Khan AA, Yurkovetskiy L, O'Grady K, Pickard JM, de Pooter R, Antonopoulos DA, Golovkina T, Chervonsky A. Polymorphic Immune Mechanisms Regulate Commensal Repertoire. Cell Rep. 2019 10 15; 29(3):541-550.e4.

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Maufort JP, Israel JS, Brown ME, Kempton SJ, Albano NJ, Zeng W, Kelnhofer LE, Reynolds MR, Perrin ES, Sanchez RJ, Sluvkin II, Thomson JA, Poore SO. Major Histocompatibility Complex-Matched Arteries Have Similar Patency to Autologous Arteries in a Mauritian Cynomolgus Macaque Major Histocompatibility Complex-Defined Transplant Model. J Am Heart Assoc. 2019 08 06; 8(15):e012135.

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Jain R, Singh S, Verma SK, Jain A. Genome-Wide Prediction of Potential Vaccine Candidates for Campylobacter jejuni Using Reverse Vaccinology. Interdiscip Sci. 2019 Sep; 11(3):337-347.

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Song I, Gil A, Mishra R, Ghersi D, Selin LK, Stern LJ. Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope. Nat Struct Mol Biol. 2017 04; 24(4):395-406.

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Parello CS, Huseby ES. Indoctrinating T cells to attack pathogens through homeschooling. Trends Immunol. 2015 Jun; 36(6):337-43.

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