Major Histocompatibility Complex

"Major Histocompatibility Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) TRANSPLANTATION ANTIGENS, genes which control the structure of the IMMUNE RESPONSE-ASSOCIATED ANTIGENS, HUMAN; the IMMUNE RESPONSE GENES which control the ability of an animal to respond immunologically to antigenic stimuli, and genes which determine the structure and/or level of the first four components of complement.

Descriptor ID	D008285
MeSH Number(s)	G05.360.340.024.340.610 G05.360.340.024.380.500 G12.500.500
Concept/Terms	Major Histocompatibility Complex Major Histocompatibility Complex Complex, Major Histocompatibility Complices, Major Histocompatibility Histocompatibility Complex, Major Histocompatibility Complices, Major Major Histocompatibility Complices Histocompatibility Complex Complex, Histocompatibility Complices, Histocompatibility Histocompatibility Complices

Below are MeSH descriptors whose meaning is more general than "Major Histocompatibility Complex".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Major Histocompatibility Complex [G05.360.340.024.340.610]
Genetic Loci [G05.360.340.024.380]
Major Histocompatibility Complex [G05.360.340.024.380.500]
Immune System Phenomena [G12]
Immunogenetic Phenomena [G12.500]
Major Histocompatibility Complex [G12.500.500]

Below are MeSH descriptors whose meaning is related to "Major Histocompatibility Complex".

Below are MeSH descriptors whose meaning is more specific than "Major Histocompatibility Complex".

Major Histocompatibility Complex
Genes, MHC Class I
Genes, MHC Class II

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Major Histocompatibility Complex" by people in this website by year, and whether "Major Histocompatibility Complex" was a major or minor topic of these publications.

Bar chart showing 50 publications over 23 distinct years, with a maximum of 5 publications in 1999 and 2006 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	1	1
1993	1	0	1
1994	1	0	1
1997	1	0	1
1998	1	1	2
1999	2	3	5
2000	0	3	3
2001	1	0	1
2003	1	2	3
2004	3	0	3
2005	2	0	2
2006	3	2	5
2007	3	1	4
2008	2	0	2
2009	3	2	5
2010	1	0	1
2011	0	2	2
2012	1	0	1
2014	1	1	2
2015	1	0	1
2017	0	2	2
2019	0	1	1
2020	1	0	1

Below are the most recent publications written about "Major Histocompatibility Complex" by people in Profiles.

Gil A, Kamga L, Chirravuri-Venkata R, Aslan N, Clark F, Ghersi D, Luzuriaga K, Selin LK. Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor ? and ? Repertoires. mBio. 2020 03 17; 11(2).

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Khan AA, Yurkovetskiy L, O'Grady K, Pickard JM, de Pooter R, Antonopoulos DA, Golovkina T, Chervonsky A. Polymorphic Immune Mechanisms Regulate Commensal Repertoire. Cell Rep. 2019 10 15; 29(3):541-550.e4.

View in: PubMed
Jain R, Singh S, Verma SK, Jain A. Genome-Wide Prediction of Potential Vaccine Candidates for Campylobacter jejuni Using Reverse Vaccinology. Interdiscip Sci. 2019 Sep; 11(3):337-347.

View in: PubMed
Song I, Gil A, Mishra R, Ghersi D, Selin LK, Stern LJ. Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope. Nat Struct Mol Biol. 2017 04; 24(4):395-406.

View in: PubMed
Parello CS, Huseby ES. Indoctrinating T cells to attack pathogens through homeschooling. Trends Immunol. 2015 Jun; 36(6):337-43.

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Keck S, Schmaler M, Ganter S, Wyss L, Oberle S, Huseby ES, Zehn D, King CG. Antigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiation. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14852-7.

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Daniels KA, Hatfield SD, Welsh RM, Brehm MA. MHC basis of T cell-dependent heterologous immunity to arenaviruses. Virology. 2014 Sep; 464-465:213-217.

View in: PubMed
Vanguri V, Govern CC, Smith R, Huseby ES. Viral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):288-93.

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Shi JQ, Chen J, Wang BR, Zhu YW, Xu Y, Wang J, Xiao H, Shi JP, Zhang YD, Xu J. Short amyloid-beta immunogens show strong immunogenicity and avoid stimulating pro-inflammatory pathways in bone marrow-derived dendritic cells from C57BL/6J mice in vitro. Peptides. 2011 Aug; 32(8):1617-25.

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Moysey RK, Li Y, Paston SJ, Baston EE, Sami MS, Cameron BJ, Gavarret J, Todorov P, Vuidepot A, Dunn SM, Pumphrey NJ, Adams KJ, Yuan F, Dennis RE, Sutton DH, Johnson AD, Brewer JE, Ashfield R, Lissin NM, Jakobsen BK. High affinity soluble ILT2 receptor: a potent inhibitor of CD8(+) T cell activation. Protein Cell. 2010 Dec; 1(12):1118-27.

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