Proto-Oncogene Proteins pp60(c-src)

"Proto-Oncogene Proteins pp60(c-src)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.

Descriptor ID	D016392
MeSH Number(s)	D08.811.913.696.620.682.725.800.630 D12.776.624.664.700.202
Concept/Terms	Proto-Oncogene Proteins pp60(c-src) Proto-Oncogene Proteins pp60(c-src) Phosphoprotein pp60(c-src) pp60 c-src c-src, pp60 pp60 c src pp60(c-src) Proto-Oncogene Protein src Protein src, Proto-Oncogene Proto Oncogene Protein src src Proto-Oncogene Product Proto-Oncogene Product, src src Proto Oncogene Product src Proto-Oncogene Protein pp60 src Proto Oncogene Protein pp60 c-src Protein pp60 Protein pp60, c-src c src Protein pp60 pp60, c-src Protein Proto-Oncogene Protein pp60(c-src)

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins pp60(c-src)".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
src-Family Kinases [D08.811.913.696.620.682.725.800]
Proto-Oncogene Proteins pp60(c-src) [D08.811.913.696.620.682.725.800.630]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Proto-Oncogene Proteins pp60(c-src) [D12.776.624.664.700.202]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogene Proteins pp60(c-src)".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins pp60(c-src)".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in this website by year, and whether "Proto-Oncogene Proteins pp60(c-src)" was a major or minor topic of these publications.

Bar chart showing 8 publications over 7 distinct years, with a maximum of 2 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2000	0	1	1
2003	1	0	1
2011	0	1	1
2012	0	2	2
2013	1	0	1
2017	0	1	1

Below are the most recent publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in Profiles.

Kemmerling N, Wunderlich P, Theil S, Linnartz-Gerlach B, Hersch N, Hoffmann B, Heneka MT, de Strooper B, Neumann H, Walter J. Intramembranous processing by ?-secretase regulates reverse signaling of ephrin-B2 in migration of microglia. Glia. 2017 07; 65(7):1103-1118.

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Katyal P, Puthenveetil R, Vinogradova O. Structural insights into the recognition of ?3 integrin cytoplasmic tail by the SH3 domain of Src kinase. Protein Sci. 2013 Oct; 22(10):1358-65.

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Gillespie E, Leeman SE, Watts LA, Coukos JA, O'Brien MJ, Cerda SR, Farraye FA, Stucchi AF. Plasminogen activator inhibitor-1 is increased in colonic epithelial cells from patients with colitis-associated cancer. J Crohns Colitis. 2013 Jun; 7(5):403-11.

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Krapf D, Ruan YC, Wertheimer EV, Battistone MA, Pawlak JB, Sanjay A, Pilder SH, Cuasnicu P, Breton S, Visconti PE. cSrc is necessary for epididymal development and is incorporated into sperm during epididymal transit. Dev Biol. 2012 Sep 01; 369(1):43-53.

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Saxena P, Trerotola M, Wang T, Li J, Sayeed A, Vanoudenhove J, Adams DS, Fitzgerald TJ, Altieri DC, Languino LR. PSA regulates androgen receptor expression in prostate cancer cells. Prostate. 2012 May 15; 72(7):769-76.

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Ziegenfuss JS, Biswas R, Avery MA, Hong K, Sheehan AE, Yeung YG, Stanley ER, Freeman MR. Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature. 2008 Jun 12; 453(7197):935-9.

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Sekimoto H, Boney CM. C-terminal Src kinase (CSK) modulates insulin-like growth factor-I signaling through Src in 3T3-L1 differentiation. Endocrinology. 2003 Jun; 144(6):2546-52.

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Zrihan-Licht S, Fu Y, Settleman J, Schinkmann K, Shaw L, Keydar I, Avraham S, Avraham H. RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion. Oncogene. 2000 Mar 02; 19(10):1318-28.

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Mao J, Xie W, Yuan H, Simon MI, Mano H, Wu D. Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13. EMBO J. 1998 Oct 01; 17(19):5638-46.

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Lee H, Trimble JJ, Yoon DW, Regier D, Desrosiers RC, Jung JU. Genetic variation of herpesvirus saimiri subgroup A transforming protein and its association with cellular src. J Virol. 1997 May; 71(5):3817-25.

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