 NADPH Oxidase
"NADPH Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein enzyme that catalyzes the univalent reduction of OXYGEN using NADPH as an electron donor to create SUPEROXIDE ANION. The enzyme is dependent on a variety of CYTOCHROMES. Defects in the production of superoxide ions by enzymes such as NADPH oxidase result in GRANULOMATOUS DISEASE, CHRONIC.
| Descriptor ID |
D019255
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| MeSH Number(s) |
D08.811.682.608.575 D12.776.331.894
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase".
This graph shows the total number of publications written about "NADPH Oxidase" by people in this website by year, and whether "NADPH Oxidase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1986 | 0 | 2 | 2 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 2 | 1 | 3 | | 1995 | 1 | 0 | 1 | | 1998 | 4 | 0 | 4 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2003 | 2 | 2 | 4 | | 2004 | 2 | 3 | 5 | | 2005 | 3 | 1 | 4 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 4 | 1 | 5 | | 2009 | 3 | 0 | 3 | | 2010 | 1 | 1 | 2 | | 2011 | 4 | 3 | 7 | | 2012 | 1 | 2 | 3 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 2 | 3 | | 2015 | 2 | 2 | 4 |
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Below are the most recent publications written about "NADPH Oxidase" by people in Profiles.
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Frazão JB, Thain A, Zhu Z, Luengo M, Condino-Neto A, Newburger PE. Regulation of CYBB Gene Expression in Human Phagocytes by a Distant Upstream NF-?B Binding Site. J Cell Biochem. 2015 Sep; 116(9):2008-17.
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Craige SM, Kant S, Reif M, Chen K, Pei Y, Angoff R, Sugamura K, Fitzgibbons T, Keaney JF. Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions. Free Radic Biol Med. 2015 Dec; 89:1-7.
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Münzel T, Gori T, Keaney JF, Maack C, Daiber A. Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications. Eur Heart J. 2015 Oct 7; 36(38):2555-64.
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Huber MJ, Basu R, Cecchettini C, Cuadra AE, Chen QH, Shan Z. Activation of the (pro)renin receptor in the paraventricular nucleus increases sympathetic outflow in anesthetized rats. Am J Physiol Heart Circ Physiol. 2015 Sep; 309(5):H880-7.
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Craige SM, Kant S, Keaney JF. Reactive oxygen species in endothelial function - from disease to adaptation - . Circ J. 2015; 79(6):1145-55.
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Conti F, Aragão Filho WC, Prando C, Deswarte C, Hubeau M, Newburger PE, Casanova JL, Bustamante J, Condino-Neto A. Phagocyte nicotinamide adenine dinucleotide phosphate oxidase activity in patients with inherited IFN-?R1 or IFN-?R2 deficiency. J Allergy Clin Immunol. 2015 May; 135(5):1393-5.e1.
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Dutra FF, Alves LS, Rodrigues D, Fernandez PL, de Oliveira RB, Golenbock DT, Zamboni DS, Bozza MT. Hemolysis-induced lethality involves inflammasome activation by heme. Proc Natl Acad Sci U S A. 2014 Sep 30; 111(39):E4110-8.
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Smith CK, Vivekanandan-Giri A, Tang C, Knight JS, Mathew A, Padilla RL, Gillespie BW, Carmona-Rivera C, Liu X, Subramanian V, Hasni S, Thompson PR, Heinecke JW, Saran R, Pennathur S, Kaplan MJ. Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus. Arthritis Rheumatol. 2014 Sep; 66(9):2532-44.
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Sokolovska A, Becker CE, Ip WK, Rathinam VA, Brudner M, Paquette N, Tanne A, Vanaja SK, Moore KJ, Fitzgerald KA, Lacy-Hulbert A, Stuart LM. Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function. Nat Immunol. 2013 Jun; 14(6):543-53.
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Chen SJ, Zhang W, Tong Q, Conrad K, Hirschler-Laszkiewicz I, Bayerl M, Kim JK, Cheung JY, Miller BA. Role of TRPM2 in cell proliferation and susceptibility to oxidative stress. Am J Physiol Cell Physiol. 2013 Mar; 304(6):C548-60.
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