The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.
Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, Pitha PM, Fitzgerald KA, Golenbock DT. The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling. J Biol Chem. 2005 Apr 29; 280(17):17005-12.
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Adaptor Proteins, Signal Transducing
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Antigens, Differentiation
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Biological Assay
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Cell Line
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DNA-Binding Proteins
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Dose-Response Relationship, Drug
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Electroporation
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Genes, Reporter
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Glutathione Transferase
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Humans
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Interferon Regulatory Factor-3
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Interferon Regulatory Factor-7
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Interferon Regulatory Factors
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Interferon Type I
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Ligands
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Lipopolysaccharides
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Membrane Glycoproteins
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Microscopy, Confocal
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Models, Biological
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Myeloid Differentiation Factor 88
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Phosphorylation
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Receptors, Cell Surface
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Receptors, Immunologic
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Recombinant Fusion Proteins
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Reverse Transcriptase Polymerase Chain Reaction
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RNA Interference
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RNA, Double-Stranded
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RNA, Small Interfering
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Signal Transduction
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Time Factors
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Toll-Like Receptor 3
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Toll-Like Receptor 4
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Toll-Like Receptor 7
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Toll-Like Receptor 8
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Toll-Like Receptors
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Transcription Factors
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Transfection