YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction.

Sweet CR, Conlon J, Golenbock DT, Goguen J, Silverman N. YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction. Cell Microbiol. 2007 Nov; 9(11):2700-15.

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subject areas

Bacterial Proteins
Cell Line
Humans
Immunoblotting
Interferon Regulatory Factor-3
Interleukin-8
MAP Kinase Kinase Kinases
Mitogen-Activated Protein Kinases
NF-kappa B
p38 Mitogen-Activated Protein Kinases
Signal Transduction
TNF Receptor-Associated Factor 3
TNF Receptor-Associated Factor 6
Toll-Like Receptor 3
Toll-Like Receptor 4
Toll-Like Receptors
Transfection
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Ubiquitin

authors with profiles

Douglas T Golenbock MD
Neal Silverman PhD