Cyclic GMP-Dependent Protein Kinase Type I
"Cyclic GMP-Dependent Protein Kinase Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA.
| Descriptor ID |
D062965
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.150.150.500 D12.644.360.200.150.500 D12.776.476.200.150.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclic GMP-Dependent Protein Kinase Type I".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP-Dependent Protein Kinase Type I".
This graph shows the total number of publications written about "Cyclic GMP-Dependent Protein Kinase Type I" by people in this website by year, and whether "Cyclic GMP-Dependent Protein Kinase Type I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cyclic GMP-Dependent Protein Kinase Type I" by people in Profiles.
-
Calamaras TD, Pande S, Baumgartner RA, Kim SK, McCarthy JC, Martin GL, Tam K, McLaughlin AL, Wang GR, Aronovitz MJ, Lin W, Aguirre JI, Baca P, Liu P, Richards DA, Davis RJ, Karas RH, Jaffe IZ, Blanton RM. MLK3 mediates impact of PKG1a on cardiac function and controls blood pressure through separate mechanisms. JCI Insight. 2021 09 22; 6(18).
-
Kim JJ, Casteel DE, Huang G, Kwon TH, Ren RK, Zwart P, Headd JJ, Brown NG, Chow DC, Palzkill T, Kim C. Co-crystal structures of PKG I? (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding. PLoS One. 2011 Apr 19; 6(4):e18413.