Cyclic GMP-Dependent Protein Kinase Type I
"Cyclic GMP-Dependent Protein Kinase Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA.
| Descriptor ID |
D062965
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| MeSH Number(s) |
D08.811.913.696.620.682.700.150.150.500 D12.644.360.200.150.500 D12.776.476.200.150.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclic GMP-Dependent Protein Kinase Type I".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP-Dependent Protein Kinase Type I".
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Below are the most recent publications written about "Cyclic GMP-Dependent Protein Kinase Type I" by people in Profiles.
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Kim JJ, Casteel DE, Huang G, Kwon TH, Ren RK, Zwart P, Headd JJ, Brown NG, Chow DC, Palzkill T, Kim C. Co-crystal structures of PKG I? (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding. PLoS One. 2011 Apr 19; 6(4):e18413.