Membrane Dynamics of ?-Secretase Provides a Molecular Basis for ?-Amyloid Binding and Processing.

Somavarapu AK, Kepp KP. Membrane Dynamics of ?-Secretase Provides a Molecular Basis for ?-Amyloid Binding and Processing. ACS Chem Neurosci. 2017 11 15; 8(11):2424-2436.

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subject areas

Alzheimer Disease
Amyloid beta-Protein Precursor
Amyloid Precursor Protein Secretases
Drug Design
Humans
Hydrophobic and Hydrophilic Interactions
Kinetics
Membrane Proteins
Models, Molecular
Molecular Docking Simulation
Presenilin-1
Principal Component Analysis
Protein Binding
Protein Conformation
Protein Processing, Post-Translational
Protein Structure, Secondary
Protein Subunits
Substrate Specificity

authors with profiles

Arun Kumar Somavarapu PhD