"Second Messenger Systems" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.
| Descriptor ID |
D015290
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| MeSH Number(s) |
G02.111.820.800 G04.835.800
|
| Concept/Terms |
Second Messenger Systems- Second Messenger Systems
- Second Messenger System
- System, Second Messenger
- Systems, Second Messenger
- Intracellular Second Messengers
- Intracellular Second Messenger
- Messengers, Intracellular Second
- Second Messenger, Intracellular
- Second Messengers, Intracellular
Second Messengers- Second Messengers
- Messenger, Second
- Messengers, Second
- Second Messenger
|
Below are MeSH descriptors whose meaning is more general than "Second Messenger Systems".
Below are MeSH descriptors whose meaning is more specific than "Second Messenger Systems".
This graph shows the total number of publications written about "Second Messenger Systems" by people in this website by year, and whether "Second Messenger Systems" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Second Messenger Systems" by people in Profiles.
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Hariharan VN, Yadav R, Thakur C, Singh A, Gopinathan R, Singh DP, Sankhe G, Malhotra V, Chandra N, Bhatt A, Saini DK. Cyclic di-GMP sensing histidine kinase PdtaS controls mycobacterial adaptation to carbon sources. FASEB J. 2021 04; 35(4):e21475.
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Roderick JE, Gallagher KM, Murphy LC, O'Connor KW, Tang K, Zhang B, Brehm MA, Greiner DL, Yu J, Zhu LJ, Green MR, Kelliher MA. Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death. Blood. 2021 01 28; 137(4):500-512.
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Hsiao WY, Guertin DA. De Novo Lipogenesis as a Source of Second Messengers in Adipocytes. Curr Diab Rep. 2019 11 20; 19(11):138.
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Hindle AG, Allen KN, Batten AJ, H?ckst?dt LA, Turner-Maier J, Schulberg SA, Johnson J, Karlsson E, Lindblad-Toh K, Costa DP, Bloch DB, Zapol WM, Buys ES. Low guanylyl cyclase activity in Weddell seals: implications for peripheral vasoconstriction and perfusion of the brain during diving. Am J Physiol Regul Integr Comp Physiol. 2019 06 01; 316(6):R704-R715.
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Nelson C, Ambros V, Baehrecke EH. miR-14 regulates autophagy during developmental cell death by targeting ip3-kinase 2. Mol Cell. 2014 Nov 06; 56(3):376-388.
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Smith SC, Joshi KK, Zik JJ, Trinh K, Kamajaya A, Chien P, Ryan KR. Cell cycle-dependent adaptor complex for ClpXP-mediated proteolysis directly integrates phosphorylation and second messenger signals. Proc Natl Acad Sci U S A. 2014 Sep 30; 111(39):14229-34.
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Ablasser A, Schmid-Burgk JL, Hemmerling I, Horvath GL, Schmidt T, Latz E, Hornung V. Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP. Nature. 2013 Nov 28; 503(7477):530-4.
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Leybaert L, Sanderson MJ. Intercellular Ca(2+) waves: mechanisms and function. Physiol Rev. 2012 Jul; 92(3):1359-92.
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Blaustein JD. Steroid hormone receptors: long- and short-term integrators of the internal milieu and the external environment. Horm Metab Res. 2012 Jul; 44(8):563-8.
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Abel S, Chien P, Wassmann P, Schirmer T, Kaever V, Laub MT, Baker TA, Jenal U. Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks. Mol Cell. 2011 Aug 19; 43(4):550-60.