Amyloid beta-Peptides

"Amyloid beta-Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.

Descriptor ID	D016229
MeSH Number(s)	D12.644.024 D12.776.049.407.249.500 D12.776.543.039.500
Concept/Terms	Amyloid beta-Peptides Amyloid beta-Peptides Amyloid beta Peptides beta-Peptides, Amyloid Alzheimer's ABP ABP, Alzheimer's Alzheimer ABP Alzheimers ABP Alzheimer's Amyloid Fibril Protein Amyloid AD-AP AD-AP, Amyloid Amyloid AD AP beta-Amyloid Protein Protein, beta-Amyloid beta Amyloid Protein Amyloid beta-Protein Amyloid beta Protein beta-Protein, Amyloid Amyloid beta-Proteins Amyloid beta Proteins beta-Proteins, Amyloid Amyloid Fibril Protein, Alzheimer's Amyloid Protein A4 Protein A4, Amyloid Alzheimer beta-Protein Alzheimer beta Protein beta-Protein, Alzheimer Amyloid beta-Peptide Amyloid beta Peptide beta-Peptide, Amyloid

Below are MeSH descriptors whose meaning is more general than "Amyloid beta-Peptides".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Amyloid beta-Peptides [D12.644.024]
Proteins [D12.776]
Amyloid [D12.776.049]
Amyloidogenic Proteins [D12.776.049.407]
Amyloid beta-Protein Precursor [D12.776.049.407.249]
Amyloid beta-Peptides [D12.776.049.407.249.500]
Membrane Proteins [D12.776.543]
Amyloid beta-Protein Precursor [D12.776.543.039]
Amyloid beta-Peptides [D12.776.543.039.500]

Below are MeSH descriptors whose meaning is related to "Amyloid beta-Peptides".

Below are MeSH descriptors whose meaning is more specific than "Amyloid beta-Peptides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Amyloid beta-Peptides" by people in this website by year, and whether "Amyloid beta-Peptides" was a major or minor topic of these publications.

Bar chart showing 167 publications over 25 distinct years, with a maximum of 20 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2001	3	0	3
2002	3	1	4
2003	1	1	2
2005	6	1	7
2006	4	2	6
2007	3	3	6
2008	4	0	4
2009	4	3	7
2010	4	4	8
2011	7	1	8
2012	3	3	6
2013	1	1	2
2014	3	3	6
2015	5	1	6
2016	2	3	5
2017	2	4	6
2018	2	4	6
2019	8	7	15
2020	4	7	11
2021	2	4	6
2022	0	11	11
2023	1	7	8
2024	9	11	20
2025	1	2	3

Below are the most recent publications written about "Amyloid beta-Peptides" by people in Profiles.

Villacampa N, Sarlus H, Martorell P, Bhalla K, Gomez-Castro S, Vieira-Saecker A, Slutzkin I, H?ndler K, Venegas C, McManus R, Ulas T, Beyer M, Segal E, Heneka MT. Proliferating Microglia Exhibit Unique Transcriptional and Functional Alterations in Alzheimer's Disease. ASN Neuro. 2025; 17(1):2506406.

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McManus RM, Komes MP, Griep A, Santarelli F, Schwartz S, Ram?n Perea J, Schlachetzki JCM, Bouvier DS, Khalil MA, Lauterbach MA, Heinemann L, Schl?ter T, Pour MS, Lovotti M, Stahl R, Duthie F, Rodr?guez-Alc?zar JF, Schmidt SV, Spitzer J, Noori P, Maillo A, Boettcher A, Herron B, McConville J, Gomez-Cabrero D, Tegn?r J, Glass CK, Hiller K, Latz E, Heneka MT. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression. Immunity. 2025 Feb 11; 58(2):326-343.e11.

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Schneider LS, Freiesleben SD, van Breukelen G, Wang X, Brosseron F, Heneka MT, Teipel S, Kleineidam L, Stark M, Roy-Kluth N, Wagner M, Spottke A, Schmid M, Roeske S, Laske C, Munk MH, Perneczky R, Rauchmann BS, Buerger K, Janowitz D, D?zel E, Glanz W, Jessen F, Rostamzadeh A, Wiltfang J, Bartels C, Kilimann I, Schneider A, Fliessbach K, Priller J, Spruth EJ, Hellmann-Regen J, Peters O. Linking higher amyloid beta 1-38 (A?(1-38)) levels to reduced Alzheimer's disease progression risk. Alzheimers Dement. 2025 Feb; 21(2):e14545.

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Schrempel S, Kottwitz AK, Piechotta A, Gnoth K, B?schgens L, Hartlage-R?bsamen M, Morawski M, Schenk M, Kleinschmidt M, Serrano GE, Beach TG, Rostagno A, Ghiso J, Heneka MT, Walter J, Wirths O, Schilling S, Ro?ner S. Identification of isoAsp7-A? as a major A? variant in Alzheimer's disease, dementia with Lewy bodies and vascular dementia. Acta Neuropathol. 2024 Dec 03; 148(1):78.

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Stark M, Wagner M, Kuhn E, B?rger K, D?zel E, Hellmann-Regen J, Heneka MT, Laske C, Perneczky R, Peters O, Priller J, Schmid M, Schneider A, Spottke A, Teipel S, Wiltfang J, Jessen F, Kleineidam L. Clinical Manifestations. Alzheimers Dement. 2024 Dec; 20 Suppl 3:e091377.

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Heneka MT, Morgan D, Jessen F. Passive anti-amyloid ? immunotherapy in Alzheimer's disease-opportunities and challenges. Lancet. 2024 11 30; 404(10468):2198-2208.

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Bell TR, Franz CE, Thomas KR, Williams ME, Eyler LT, Lerman I, Fennema-Notestine C, Puckett OK, Dorros SM, Panizzon MS, Pearce RC, Hagler DJ, Lyons MJ, Elman JA, Kremen WS. Elevated C-Reactive Protein in Older Men With Chronic Pain: Association With Plasma Amyloid Levels and Hippocampal Volume. J Gerontol A Biol Sci Med Sci. 2024 Nov 01; 79(11).

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Liu S, Park T, Kr?ger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers. Alzheimers Dement. 2024 Nov; 20(11):7698-7714.

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Botella Lucena P, Heneka MT. Inflammatory aspects of Alzheimer's disease. Acta Neuropathol. 2024 Aug 28; 148(1):31.

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Wang X, Campbell B, Bodogai M, McDevitt RA, Patrikeev A, Gusev F, Ragonnaud E, Kumaraswami K, Shirenova S, Vardy K, Alameh MG, Weissman D, Ishikawa-Ankerhold H, Okun E, Rogaev E, Biragyn A. CD8+ T cells exacerbate AD-like symptoms in mouse model of amyloidosis. Brain Behav Immun. 2024 Nov; 122:444-455.

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