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PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation.
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PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation.
Lee KY, D'Acquisto F, Hayden MS, Shim JH, Ghosh S. PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Science. 2005 Apr 01; 308(5718):114-8.
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subject areas
3-Phosphoinositide-Dependent Protein Kinases
Adaptor Proteins, Signal Transducing
Apoptosis Regulatory Proteins
B-Cell CLL-Lymphoma 10 Protein
CARD Signaling Adaptor Proteins
Carrier Proteins
Caspases
Cell Line
Cell Line, Tumor
Enzyme Activation
Guanylate Cyclase
Humans
I-kappa B Kinase
Isoenzymes
Jurkat Cells
Lymphocyte Activation
Lymphoma, B-Cell, Marginal Zone
Membrane Microdomains
Membrane Proteins
Models, Biological
Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
Neoplasm Proteins
NF-kappa B
Phosphatidylinositol 3-Kinases
Phosphorylation
Protein Kinase C
Protein Kinase C-theta
Receptors, Antigen, T-Cell
RNA Interference
Signal Transduction
T-Lymphocytes
Transfection
authors with profiles
Jae-Hyuck Shim PhD