Heterogeneous-Nuclear Ribonucleoprotein K
"Heterogeneous-Nuclear Ribonucleoprotein K" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
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A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Descriptor ID |
D034641
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MeSH Number(s) |
D12.776.157.725.813.750.500 D12.776.260.268 D12.776.664.962.813.750.500
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Concept/Terms |
hnRNP K Protein- hnRNP K Protein
- Heterogeneous Nuclear Ribonucleoprotein Particle K Protein
- dC-Stretch-Binding Protein
- dC Stretch Binding Protein
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Below are MeSH descriptors whose meaning is more general than "Heterogeneous-Nuclear Ribonucleoprotein K".
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This graph shows the total number of publications written about "Heterogeneous-Nuclear Ribonucleoprotein K" by people in this website by year, and whether "Heterogeneous-Nuclear Ribonucleoprotein K" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterogeneous-Nuclear Ribonucleoprotein K" by people in Profiles.
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Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, Khalil AM, Zuk O, Amit I, Rabani M, Attardi LD, Regev A, Lander ES, Jacks T, Rinn JL. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 2010 Aug 06; 142(3):409-19.