TCF Transcription Factors

"TCF Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.

Descriptor ID	D051820
MeSH Number(s)	D12.776.260.730 D12.776.660.235.400.800 D12.776.664.235.400.800 D12.776.930.875
Concept/Terms	TCF Transcription Factors TCF Transcription Factors Transcription Factors, TCF Lymphoid Enhancer Factors T-Cell Factors T Cell Factors LEF Transcription Factors Transcription Factors, LEF

Below are MeSH descriptors whose meaning is more general than "TCF Transcription Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
TCF Transcription Factors [D12.776.260.730]
Nuclear Proteins [D12.776.660]
Chromosomal Proteins, Non-Histone [D12.776.660.235]
High Mobility Group Proteins [D12.776.660.235.400]
TCF Transcription Factors [D12.776.660.235.400.800]
Nucleoproteins [D12.776.664]
Chromosomal Proteins, Non-Histone [D12.776.664.235]
High Mobility Group Proteins [D12.776.664.235.400]
TCF Transcription Factors [D12.776.664.235.400.800]
Transcription Factors [D12.776.930]
TCF Transcription Factors [D12.776.930.875]

Below are MeSH descriptors whose meaning is related to "TCF Transcription Factors".

Below are MeSH descriptors whose meaning is more specific than "TCF Transcription Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "TCF Transcription Factors" by people in this website by year, and whether "TCF Transcription Factors" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1999 and 2001 and 2004 and 2005 and 2007 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2001	0	1	1
2004	0	1	1
2005	1	0	1
2007	0	1	1
2021	1	0	1

Below are the most recent publications written about "TCF Transcription Factors" by people in Profiles.

Chun N, Ang RL, Chan M, Fairchild RL, Baldwin WM, Horwitz JK, Gelles JD, Chipuk JE, Kelliher MA, Pavlov VI, Li Y, Homann D, Heeger PS, Ting AT. T cell-derived tumor necrosis factor induces cytotoxicity by activating RIPK1-dependent target cell death. JCI Insight. 2021 12 22; 6(24).

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Ray SK, Leiter AB. The basic helix-loop-helix transcription factor NeuroD1 facilitates interaction of Sp1 with the secretin gene enhancer. Mol Cell Biol. 2007 Nov; 27(22):7839-47.

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Dong YF, Soung do Y, Chang Y, Enomoto-Iwamoto M, Paris M, O'Keefe RJ, Schwarz EM, Drissi H. Transforming growth factor-beta and Wnt signals regulate chondrocyte differentiation through Twist1 in a stage-specific manner. Mol Endocrinol. 2007 Nov; 21(11):2805-20.

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Kapoor A, Li HJ, Leiter AB. Intestinal development: the many faces of Wnt signaling. Gastroenterology. 2007 Aug; 133(2):710-2.

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Kim BM, Mao J, Taketo MM, Shivdasani RA. Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology. 2007 Aug; 133(2):529-38.

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Dong YF, Soung do Y, Schwarz EM, O'Keefe RJ, Drissi H. Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. J Cell Physiol. 2006 Jul; 208(1):77-86.

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Borghesi L, Aites J, Nelson S, Lefterov P, James P, Gerstein R. E47 is required for V(D)J recombinase activity in common lymphoid progenitors. J Exp Med. 2005 Dec 19; 202(12):1669-77.

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Dong Y, Drissi H, Chen M, Chen D, Zuscik MJ, Schwarz EM, O'Keefe RJ. Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta. J Cell Biochem. 2005 Aug 01; 95(5):1057-68.

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O'Neil J, Shank J, Cusson N, Murre C, Kelliher M. TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. Cancer Cell. 2004 Jun; 5(6):587-96.

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O'Neil J, Billa M, Oikemus S, Kelliher M. The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice. Oncogene. 2001 Jun 28; 20(29):3897-905.

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