"Calnexin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lectin found in ENDOPLASMIC RETICULUM membranes that binds to specific N-linked OLIGOSACCHARIDES found on newly synthesized proteins. It may play role in PROTEIN FOLDING or retention and degradation of misfolded proteins in the endoplasmic reticulum.
| Descriptor ID |
D037281
|
| MeSH Number(s) |
D12.644.360.372.311 D12.776.157.125.412.311 D12.776.476.387.311 D12.776.503.295 D12.776.543.162
|
| Concept/Terms |
Calnexin- Calnexin
- Phosphoprotein pp90
- pp90, Phosphoprotein
- IP90 Protein
- Integral Membrane Protein IP90
|
Below are MeSH descriptors whose meaning is more general than "Calnexin".
Below are MeSH descriptors whose meaning is more specific than "Calnexin".
This graph shows the total number of publications written about "Calnexin" by people in this website by year, and whether "Calnexin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Calnexin" by people in Profiles.
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W?thrich M, Brandhorst TT, Sullivan TD, Filutowicz H, Sterkel A, Stewart D, Li M, Lerksuthirat T, LeBert V, Shen ZT, Ostroff G, Deepe GS, Hung CY, Cole G, Walter JA, Jenkins MK, Klein B. Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes. Cell Host Microbe. 2015 Apr 08; 17(4):452-65.
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Bouchecareilh M, Hutt DM, Szajner P, Flotte TR, Balch WE. Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of a1-antitrypsin deficiency. J Biol Chem. 2012 Nov 02; 287(45):38265-78.
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Barbagallo B, Prescott HA, Boyle P, Climer J, Francis MM. A dominant mutation in a neuronal acetylcholine receptor subunit leads to motor neuron degeneration in Caenorhabditis elegans. J Neurosci. 2010 Oct 20; 30(42):13932-42.
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Svedine S, Wang T, Halaban R, Hebert DN. Carbohydrates act as sorting determinants in ER-associated degradation of tyrosinase. J Cell Sci. 2004 Jun 15; 117(Pt 14):2937-49.
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McGinnes LW, Morrison TG. Role of carbohydrate processing and calnexin binding in the folding and activity of the HN protein of Newcastle disease virus. Virus Res. 1998 Feb; 53(2):175-85.