 Neoplasm Proteins
"Neoplasm Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (TUMOR MARKERS, BIOLOGICAL) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
| Descriptor ID |
D009363
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| MeSH Number(s) |
D12.776.624
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neoplasm Proteins".
Below are MeSH descriptors whose meaning is more specific than "Neoplasm Proteins".
This graph shows the total number of publications written about "Neoplasm Proteins" by people in this website by year, and whether "Neoplasm Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1983 | 0 | 1 | 1 | | 1986 | 1 | 0 | 1 | | 1987 | 0 | 1 | 1 | | 1991 | 1 | 1 | 2 | | 1992 | 1 | 1 | 2 | | 1993 | 1 | 1 | 2 | | 1994 | 2 | 1 | 3 | | 1995 | 5 | 0 | 5 | | 1996 | 1 | 1 | 2 | | 1997 | 3 | 1 | 4 | | 1998 | 2 | 1 | 3 | | 1999 | 5 | 2 | 7 | | 2000 | 2 | 1 | 3 | | 2001 | 4 | 0 | 4 | | 2002 | 12 | 3 | 15 | | 2003 | 13 | 3 | 16 | | 2004 | 9 | 6 | 15 | | 2005 | 2 | 10 | 12 | | 2006 | 7 | 5 | 12 | | 2007 | 7 | 3 | 10 | | 2008 | 8 | 1 | 9 | | 2009 | 3 | 1 | 4 | | 2010 | 3 | 2 | 5 | | 2011 | 6 | 1 | 7 | | 2012 | 7 | 3 | 10 | | 2013 | 4 | 1 | 5 | | 2014 | 2 | 2 | 4 | | 2015 | 4 | 4 | 8 | | 2016 | 3 | 1 | 4 | | 2017 | 1 | 3 | 4 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neoplasm Proteins" by people in Profiles.
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Swenson SA, Gilbreath TJ, Vahle H, Hynes-Smith RW, Graham JH, Law HC, Amador C, Woods NT, Green MR, Buckley SM. UBR5 HECT domain mutations identified in mantle cell lymphoma control maturation of B cells. Blood. 2020 07 16; 136(3):299-312.
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Goyal A, Patel S, Goyal K, Morgan EA, Foreman RK. Variable loss of CD30 expression by immunohistochemistry in recurrent cutaneous CD30+ lymphoid neoplasms treated with brentuximab vedotin. J Cutan Pathol. 2019 Nov; 46(11):823-829.
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Dagbay KB, Hill ME, Barrett E, Hardy JA. Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency. Biochemistry. 2017 08 29; 56(34):4568-4577.
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Dowdle ME, Imboden SB, Park S, Ryder SP, Sheets MD. Horizontal Gel Electrophoresis for Enhanced Detection of Protein-RNA Complexes. J Vis Exp. 2017 07 28; (125).
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Elkhatib RA, Paci M, Boissier R, Longepied G, Auguste Y, Achard V, Bourgeois P, Levy N, Branger N, Mitchell MJ, Metzler-Guillemain C. LEM-domain proteins are lost during human spermiogenesis but BAF and BAF-L persist. Reproduction. 2017 Oct; 154(4):387-401.
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Shearer AE, Eppsteiner RW, Frees K, Tejani V, Sloan-Heggen CM, Brown C, Abbas P, Dunn C, Hansen MR, Gantz BJ, Smith RJH. Genetic variants in the peripheral auditory system significantly affect adult cochlear implant performance. Hear Res. 2017 05; 348:138-142.
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Zage PE, Whittle SB, Shohet JM. CD114: A New Member of the Neural Crest-Derived Cancer Stem Cell Marker Family. J Cell Biochem. 2017 02; 118(2):221-231.
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Yang Y, Kelly P, Shaffer AL, Schmitz R, Yoo HM, Liu X, Huang da W, Webster D, Young RM, Nakagawa M, Ceribelli M, Wright GW, Yang Y, Zhao H, Yu X, Xu W, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza L, Staudt LM. Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma. Cancer Cell. 2016 Apr 11; 29(4):494-507.
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Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, Cahill S, Clark RA, Cooke VG, Davids MS, DeAngelo DJ, Dorfman DM, Eaton H, Ebert BL, Etchin J, Firestone B, Fisher DC, Freedman AS, Galinsky IA, Gao H, Garcia JS, Garnache-Ottou F, Graubert TA, Gutierrez A, Halilovic E, Harris MH, Herbert ZT, Horwitz SM, Inghirami G, Intlekoffer AM, Ito M, Izraeli S, Jacobsen ED, Jacobson CA, Jeay S, Jeremias I, Kelliher MA, Koch R, Konopleva M, Kopp N, Kornblau SM, Kung AL, Kupper TS, LaBoeuf N, LaCasce AS, Lees E, Li LS, Look AT, Murakami M, Muschen M, Neuberg D, Ng SY, Odejide OO, Orkin SH, Paquette RR, Place AE, Roderick JE, Ryan JA, Sallan SE, Shoji B, Silverman LB, Soiffer RJ, Steensma DP, Stegmaier K, Stone RM, Tamburini J, Thorner AR, van Hummelen P, Wadleigh M, Wiesmann M, Weng AP, Wuerthner JU, Williams DA, Wollison BM, Lane AA, Letai A, Bertagnolli MM, Ritz J, Brown M, Long H, Aster JC, Shipp MA, Griffin JD, Weinstock DM. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 2016 Apr 11; 29(4):574-86.
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Becker MA, Ibrahim YH, Oh AS, Fagan DH, Byron SA, Sarver AL, Lee AV, Shaw LM, Fan C, Perou CM, Yee D. Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer. PLoS One. 2016; 11(3):e0150564.
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