CRISPR-Associated Proteins

"CRISPR-Associated Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.

Descriptor ID	D064130
MeSH Number(s)	D12.776.212
Concept/Terms	CRISPR-Associated Proteins CRISPR-Associated Proteins CRISPR Associated Proteins Proteins, CRISPR-Associated CRISPR-Associated Protein Complex Proteins CRISPR-Associated Protein Complex Proteins CRISPR Associated Protein Complex Proteins CRISPR-Associated Complex for Antiviral Defense Proteins CRISPR Associated Complex for Antiviral Defense Proteins CASCADE Proteins, CRISPR-Associated CASCADE Proteins, CRISPR Associated CRISPR-Associated CASCADE Proteins Repeat-Associated Mysterious Proteins Repeat-Associated Mysterious Proteins Proteins, Repeat-Associated Mysterious Repeat Associated Mysterious Proteins

Below are MeSH descriptors whose meaning is more general than "CRISPR-Associated Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
CRISPR-Associated Proteins [D12.776.212]

Below are MeSH descriptors whose meaning is related to "CRISPR-Associated Proteins".

Below are MeSH descriptors whose meaning is more specific than "CRISPR-Associated Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CRISPR-Associated Proteins" by people in this website by year, and whether "CRISPR-Associated Proteins" was a major or minor topic of these publications.

Bar chart showing 13 publications over 6 distinct years, with a maximum of 7 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2014	4	3	7
2015	1	0	1
2016	1	0	1
2017	1	0	1
2019	1	0	1
2020	1	1	2

Below are the most recent publications written about "CRISPR-Associated Proteins" by people in Profiles.

Barrangou R, Sontheimer EJ. Shutting down RNA-targeting CRISPR. Science. 2020 07 03; 369(6499):31-32.

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Davidson AR, Lu WT, Stanley SY, Wang J, Mejdani M, Trost CN, Hicks BT, Lee J, Sontheimer EJ. Anti-CRISPRs: Protein Inhibitors of CRISPR-Cas Systems. Annu Rev Biochem. 2020 06 20; 89:309-332.

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Iyer S, Suresh S, Guo D, Daman K, Chen JCJ, Liu P, Zieger M, Luk K, Roscoe BP, Mueller C, King OD, Emerson CP, Wolfe SA. Precise therapeutic gene correction by a simple nuclease-induced double-stranded break. Nature. 2019 04; 568(7753):561-565.

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Mir A, Edraki A, Lee J, Sontheimer EJ. Type II-C CRISPR-Cas9 Biology, Mechanism, and Application. ACS Chem Biol. 2018 02 16; 13(2):357-365.

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Sontheimer EJ, Marraffini LA. RNA. CRISPR goes retro. Science. 2016 Feb 26; 351(6276):920-1.

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Bolukbasi MF, Gupta A, Oikemus S, Derr AG, Garber M, Brodsky MH, Zhu LJ, Wolfe SA. DNA-binding-domain fusions enhance the targeting range and precision of Cas9. Nat Methods. 2015 Dec; 12(12):1150-6.

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S?nchez-Rivera FJ, Papagiannakopoulos T, Romero R, Tammela T, Bauer MR, Bhutkar A, Joshi NS, Subbaraj L, Bronson RT, Xue W, Jacks T. Rapid modelling of cooperating genetic events in cancer through somatic genome editing. Nature. 2014 Dec 18; 516(7531):428-31.

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Zhu LJ, Holmes BR, Aronin N, Brodsky MH. CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems. PLoS One. 2014; 9(9):e108424.

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Zhang Y, Sontheimer EJ. Structural biology. Cascading into focus. Science. 2014 Sep 19; 345(6203):1452-3.

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Kim H, Ishidate T, Ghanta KS, Seth M, Conte D, Shirayama M, Mello CC. A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans. Genetics. 2014 Aug; 197(4):1069-80.

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