"Neurofibromin 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane protein homologous to the ERM (Ezrin-Radixin-Moesin) family of cytoskeleton-associated proteins which regulate physical properties of membranes. Alterations in neurofibromin 2 are the cause of NEUROFIBROMATOSIS 2.
Descriptor ID |
D025581
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MeSH Number(s) |
D12.776.543.685 D12.776.624.776.612
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Concept/Terms |
Neurofibromin 2- Neurofibromin 2
- Moesin-Ezrin-Radixin-Like Protein
- Moesin Ezrin Radixin Like Protein
- Schwannomin Protein
- Protein, Schwannomin
- Neurofibromatosis Type 2 Protein
- NF2 Gene Product
- Gene Product, NF2
- Schwannomin
- Merlin
- Neurofibromatosis 2 Gene Product
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Below are MeSH descriptors whose meaning is more general than "Neurofibromin 2".
Below are MeSH descriptors whose meaning is more specific than "Neurofibromin 2".
This graph shows the total number of publications written about "Neurofibromin 2" by people in this website by year, and whether "Neurofibromin 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurofibromin 2" by people in Profiles.
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Das A, Martinez Santos JL, Alshareef M, Porto GBF, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D. In?Vitro Effect of Dovitinib (TKI258), a Multi-Target Angiokinase Inhibitor on Aggressive Meningioma Cells. Cancer Invest. 2020 Jul; 38(6):349-355.
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Joehanes R, Ying S, Huan T, Johnson AD, Raghavachari N, Wang R, Liu P, Woodhouse KA, Sen SK, Tanriverdi K, Courchesne P, Freedman JE, O'Donnell CJ, Levy D, Munson PJ. Gene expression signatures of coronary heart disease. Arterioscler Thromb Vasc Biol. 2013 Jun; 33(6):1418-26.
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Thaxton C, Bott M, Walker B, Sparrow NA, Lambert S, Fernandez-Valle C. Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length. Mol Cell Neurosci. 2011 May; 47(1):1-9.
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Kalamarides M, Stemmer-Rachamimov AO, Takahashi M, Han ZY, Chareyre F, Niwa-Kawakita M, Black PM, Carroll RS, Giovannini M. Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations. Brain Pathol. 2008 Jan; 18(1):62-70.