 Protein Binding
"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
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| MeSH Number(s) |
G02.111.087.680 G02.149.115.680 G03.495.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 0 | 4 | 4 | | 1983 | 0 | 1 | 1 | | 1985 | 0 | 3 | 3 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 3 | 3 | | 1990 | 0 | 5 | 5 | | 1991 | 0 | 5 | 5 | | 1992 | 0 | 3 | 3 | | 1993 | 0 | 4 | 4 | | 1994 | 0 | 11 | 11 | | 1995 | 0 | 11 | 11 | | 1996 | 0 | 8 | 8 | | 1997 | 0 | 12 | 12 | | 1998 | 0 | 12 | 12 | | 1999 | 0 | 16 | 16 | | 2000 | 0 | 20 | 20 | | 2001 | 0 | 31 | 31 | | 2002 | 2 | 48 | 50 | | 2003 | 0 | 48 | 48 | | 2004 | 2 | 51 | 53 | | 2005 | 1 | 44 | 45 | | 2006 | 1 | 55 | 56 | | 2007 | 0 | 56 | 56 | | 2008 | 0 | 63 | 63 | | 2009 | 0 | 62 | 62 | | 2010 | 0 | 58 | 58 | | 2011 | 1 | 57 | 58 | | 2012 | 2 | 69 | 71 | | 2013 | 0 | 61 | 61 | | 2014 | 1 | 60 | 61 | | 2015 | 0 | 58 | 58 | | 2016 | 0 | 13 | 13 | | 2017 | 0 | 16 | 16 | | 2018 | 0 | 7 | 7 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Chen S, Wang R, Zheng D, Zhang H, Chang X, Wang K, Li W, Fan J, Tian B, Cheng H. The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export. Mol Cell. 2019 04 04; 74(1):118-131.e7.
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Shen K, Sabatini DM. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):9545-9550.
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Das DK, Govindan R, Nikic-Spiegel I, Krammer F, Lemke EA, Munro JB. Direct Visualization of the Conformational Dynamics of Single Influenza Hemagglutinin Trimers. Cell. 2018 08 09; 174(4):926-937.e12.
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Ng SY, Yoshida N, Christie AL, Ghandi M, Dharia NV, Dempster J, Murakami M, Shigemori K, Morrow SN, Van Scoyk A, Cordero NA, Stevenson KE, Puligandla M, Haas B, Lo C, Meyers R, Gao G, Cherniack A, Louissaint A, Nardi V, Thorner AR, Long H, Qiu X, Morgan EA, Dorfman DM, Fiore D, Jang J, Epstein AL, Dogan A, Zhang Y, Horwitz SM, Jacobsen ED, Santiago S, Ren JG, Guerlavais V, Annis DA, Aivado M, Saleh MN, Mehta A, Tsherniak A, Root D, Vazquez F, Hahn WC, Inghirami G, Aster JC, Weinstock DM, Koch R. Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models. Nat Commun. 2018 05 22; 9(1):2024.
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Shen K, Huang RK, Brignole EJ, Condon KJ, Valenstein ML, Chantranupong L, Bomaliyamu A, Choe A, Hong C, Yu Z, Sabatini DM. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes. Nature. 2018 04 05; 556(7699):64-69.
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Ma X, Lu M, Gorman J, Terry DS, Hong X, Zhou Z, Zhao H, Altman RB, Arthos J, Blanchard SC, Kwong PD, Munro JB, Mothes W. HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations. Elife. 2018 03 21; 7.
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Wu KJ, Zhang J, Baranowski C, Leung V, Rego EH, Morita YS, Rubin EJ, Boutte CC. Characterization of Conserved and Novel Septal Factors in Mycobacterium smegmatis. J Bacteriol. 2018 03 15; 200(6).
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Morger D, Zosel F, Bühlmann M, Züger S, Mittelviefhaus M, Schuler B, Luban J, Grütter MG. The Three-Fold Axis of the HIV-1 Capsid Lattice Is the Species-Specific Binding Interface for TRIM5a. J Virol. 2018 03 01; 92(5).
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Labbadia J, Brielmann RM, Neto MF, Lin YF, Haynes CM, Morimoto RI. Mitochondrial Stress Restores the Heat Shock Response and Prevents Proteostasis Collapse during Aging. Cell Rep. 2017 Nov 07; 21(6):1481-1494.
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Shen K, Choe A, Sabatini DM. Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability. Mol Cell. 2017 Nov 02; 68(3):552-565.e8.
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