DNA-Binding Proteins

"DNA-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.

Descriptor ID	D004268
MeSH Number(s)	D12.776.260
Concept/Terms	DNA-Binding Proteins DNA-Binding Proteins DNA Binding Proteins DNA Binding Protein Binding Protein, DNA Single-Stranded DNA Binding Proteins Single-Stranded DNA Binding Proteins Single Stranded DNA Binding Proteins SS DNA BP DNA Single-Stranded Binding Protein DNA Single Stranded Binding Protein Single-Stranded DNA-Binding Protein DNA-Binding Protein, Single-Stranded Single Stranded DNA Binding Protein DNA Helix Destabilizing Proteins DNA Helix Destabilizing Proteins

Below are MeSH descriptors whose meaning is more general than "DNA-Binding Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]

Below are MeSH descriptors whose meaning is related to "DNA-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "DNA-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA-Binding Proteins" by people in this website by year, and whether "DNA-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 870 publications over 31 distinct years, with a maximum of 64 publications in 2002 and 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	14	3	17
1996	13	7	20
1997	14	7	21
1998	20	6	26
1999	25	8	33
2000	18	8	26
2001	19	10	29
2002	36	28	64
2003	20	18	38
2004	41	23	64
2005	33	18	51
2006	16	9	25
2007	14	14	28
2008	17	16	33
2009	15	14	29
2010	14	23	37
2011	18	9	27
2012	25	19	44
2013	19	16	35
2014	20	21	41
2015	23	12	35
2016	15	11	26
2017	8	6	14
2018	15	8	23
2019	12	9	21
2020	17	5	22
2021	6	10	16
2022	2	3	5
2023	0	7	7
2024	4	4	8
2025	3	2	5

Below are the most recent publications written about "DNA-Binding Proteins" by people in Profiles.

Guo S, Hu X, Cotton JL, Ma L, Li Q, Cui J, Wang Y, Thakare RP, Tao Z, Ip YT, Wu X, Wang J, Mao J. VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300. Elife. 2025 May 08; 13.

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Samejima K, Gibcus JH, Abraham S, Cisneros-Soberanis F, Samejima I, Beckett AJ, Pucekov? N, Abad MA, Spanos C, Medina-Pritchard B, Paulson JR, Xie L, Jeyaprakash AA, Prior IA, Mirny LA, Dekker J, Goloborodko A, Earnshaw WC. Rules of engagement for condensins and cohesins guide mitotic chromosome formation. Science. 2025 04 11; 388(6743):eadq1709.

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Hildebrand EM, Cowell IG, Khazeem MM, Sambare S, Uyan O, Dekker J, Austin CA. TOP2B is required for compartment strength changes upon retinoic acid treatment in SH-SY5Y cells. Chromosome Res. 2025 Apr 04; 33(1):5.

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Whalen JM, Earley J, Wisniewski C, Mercurio AM, Cantor SB. Targeting BRCA1-deficient PARP inhibitor-resistant cells with nickases reveals nick resection as a cancer vulnerability. Nat Cancer. 2025 Feb; 6(2):278-291.

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Ehrens A, Lenz B, Nieto-P?rez C, Latz E, Schmidt FI, Hoerauf A, H?bner MP. Litomosoides sigmodontis microfilariae-induced eosinophil ETosis is dependent on the canonical inflammasome pathway. Cell Rep. 2025 01 28; 44(1):115164.

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Mackness BC, Morgan BR, Deveau LM, Kathuria SV, Zitzewitz JA, Massi F. A Hydrophobic Core Stabilizes the Residual Structure in the RRM2 Intermediate State of the ALS-linked Protein TDP-43. J Mol Biol. 2024 Nov 15; 436(22):168823.

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Flynn MJ, Harper NW, Li R, Zhu LJ, Lee MJ, Benanti JA. Calcineurin promotes adaptation to chronic stress through two distinct mechanisms. Mol Biol Cell. 2024 Oct 01; 35(10):ar123.

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Chatterjee M, ?zdemir S, Fritz C, M?bius W, Kleineidam L, Mandelkow E, Biernat J, Dogdu C, Peters O, Cosma NC, Wang X, Schneider LS, Priller J, Spruth E, K?hn AA, Krause P, Klockgether T, Vogt IR, Kimmich O, Spottke A, Hoffmann DC, Fliessbach K, Miklitz C, McCormick C, Weydt P, Falkenburger B, Brandt M, Guenther R, Dinter E, Wiltfang J, Hansen N, B?hr M, Zerr I, Fl?el A, Nestor PJ, D?zel E, Glanz W, Incesoy E, B?rger K, Janowitz D, Perneczky R, Rauchmann BS, Hopfner F, Wagemann O, Levin J, Teipel S, Kilimann I, Goerss D, Prudlo J, Gasser T, Brockmann K, Mengel D, Zimmermann M, Synofzik M, Wilke C, Selma-Gonz?lez J, Turon-Sans J, Santos-Santos MA, Alcolea D, Rubio-Guerra S, Fortea J, Carbayo ?, Lle? A, Rojas-Garc?a R, Ill?n-Gala I, Wagner M, Frommann I, Roeske S, Bertram L, Heneka MT, Brosseron F, Ramirez A, Schmid M, Beschorner R, Halle A, Herms J, Neumann M, Barth?lemy NR, Bateman RJ, Rizzu P, Heutink P, Dols-Icardo O, H?glinger G, Hermann A, Schneider A. Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS. Nat Med. 2024 Jun; 30(6):1771-1783.

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Olea-Flores M, Sharma T, Verdejo-Torres O, DiBartolomeo I, Thompson PR, Padilla-Benavides T, Imbalzano AN. Muscle-specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation. FASEB J. 2024 Jun 15; 38(11):e23702.

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Hu P, Xiao H, Elmore S, Agosto-Burgos C, Hu Y, Hogan SL, Ciavatta DJ, Falk RJ, Jennette JC, Free ME. Regulatory T cells effectively downregulate the autoimmune anti-MPO response and ameliorate anti-MPO induced glomerulonephritis in mice. J Autoimmun. 2024 07; 147:103266.

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