Nuclear Receptor Coactivators
"Nuclear Receptor Coactivators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that enhance gene expression when associated with ligand bound activated NUCLEAR RECEPTORS. The coactivators may act through an enzymatic process that affects the rate of transcription or the structure of chromatin. Alternatively nuclear receptor coactivators can function as adaptor proteins that bring nuclear receptors into close proximity with transcriptional complexes.
Descriptor ID |
D056918
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MeSH Number(s) |
D12.644.360.024.314 D12.776.157.057.080 D12.776.476.024.394 D12.776.660.675 D12.776.930.617
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Coactivators".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Coactivators".
This graph shows the total number of publications written about "Nuclear Receptor Coactivators" by people in this website by year, and whether "Nuclear Receptor Coactivators" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Coactivators" by people in Profiles.
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Karlsson E, Lindberg A, Andersson E, Jemth P. High affinity between CREBBP/p300 and NCOA evolved in vertebrates. Protein Sci. 2020 07; 29(7):1687-1691.
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Yu L, Croze E, Yamaguchi KD, Tran T, Reder AT, Litvak V, Volkert MR. Induction of a unique isoform of the NCOA7 oxidation resistance gene by interferon ?-1b. J Interferon Cytokine Res. 2015 Mar; 35(3):186-99.
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Durand M, Kolpak A, Farrell T, Elliott NA, Shao W, Brown M, Volkert MR. The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins. BMC Cell Biol. 2007 Mar 28; 8:13.
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Zhang C, Dowd DR, Staal A, Gu C, Lian JB, van Wijnen AJ, Stein GS, MacDonald PN. Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing. J Biol Chem. 2003 Sep 12; 278(37):35325-36.