Syk Kinase

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"Syk Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.

Descriptor ID	D000072377
MeSH Number(s)	D08.811.913.696.620.682.725.650 D12.644.360.900 D12.776.476.913
Concept/Terms	Syk Kinase Syk Kinase Kinase, Syk SYK Tyrosine Kinase Kinase, SYK Tyrosine Tyrosine Kinase, SYK Spleen Tyrosine Kinase Kinase, Spleen Tyrosine Tyrosine Kinase, Spleen

Below are MeSH descriptors whose meaning is more general than "Syk Kinase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Syk Kinase [D08.811.913.696.620.682.725.650]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Syk Kinase [D12.644.360.900]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Syk Kinase [D12.776.476.913]

Below are MeSH descriptors whose meaning is related to "Syk Kinase".

Below are MeSH descriptors whose meaning is more specific than "Syk Kinase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Syk Kinase" by people in this website by year, and whether "Syk Kinase" was a major or minor topic of these publications.

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Below are the most recent publications written about "Syk Kinase" by people in Profiles.

Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, W?lchli S, Green MR, Tr?en G, Liest?l K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R. Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling. Blood. 2017 02 09; 129(6):759-770.

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Hang L, Blum AM, Kumar S, Urban JF, Mitreva M, Geary TG, Jardim A, Stevenson MM, Lowell CA, Weinstock JV. Downregulation of the Syk Signaling Pathway in Intestinal Dendritic Cells Is Sufficient To Induce Dendritic Cells That Inhibit Colitis. J Immunol. 2016 10 01; 197(7):2948-57.

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Bukong TN, Iracheta-Vellve A, Saha B, Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Catalano D, Kodys K, Szabo G. Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease. Hepatology. 2016 10; 64(4):1057-71.

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Bukong TN, Iracheta-Vellve A, Gyongyosi B, Ambade A, Catalano D, Kodys K, Szabo G. Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice. Alcohol Clin Exp Res. 2016 07; 40(7):1524-30.

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Bukong TN, Kodys K, Szabo G. Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection. Hepatology. 2013 Nov; 58(5):1569-79.

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Ziegenfuss JS, Biswas R, Avery MA, Hong K, Sheehan AE, Yeung YG, Stanley ER, Freeman MR. Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature. 2008 Jun 12; 453(7197):935-9.

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Damania B, DeMaria M, Jung JU, Desrosiers RC. Activation of lymphocyte signaling by the R1 protein of rhesus monkey rhadinovirus. J Virol. 2000 Mar; 74(6):2721-30.

View in: PubMed

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