 RNA Stability
"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.
| Descriptor ID |
D020871
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| MeSH Number(s) |
G02.111.780
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| Concept/Terms |
mRNA Degradation- mRNA Degradation
- Degradation, mRNA
- mRNA Transcript Degradation
- Degradation, mRNA Transcript
- Transcript Degradation, mRNA
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Below are MeSH descriptors whose meaning is more general than "RNA Stability".
Below are MeSH descriptors whose meaning is more specific than "RNA Stability".
This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 2 | 3 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 4 | 5 | | 2004 | 1 | 2 | 3 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 5 | 6 | | 2008 | 4 | 2 | 6 | | 2009 | 1 | 3 | 4 | | 2010 | 4 | 2 | 6 | | 2011 | 1 | 3 | 4 | | 2012 | 3 | 2 | 5 | | 2013 | 3 | 2 | 5 | | 2014 | 2 | 1 | 3 | | 2015 | 0 | 4 | 4 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA Stability" by people in Profiles.
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Mauger DM, Cabral BJ, Presnyak V, Su SV, Reid DW, Goodman B, Link K, Khatwani N, Reynders J, Moore MJ, McFadyen IJ. mRNA structure regulates protein expression through changes in functional half-life. Proc Natl Acad Sci U S A. 2019 11 26; 116(48):24075-24083.
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Wang R, Zheng D, Yehia G, Tian B. A compendium of conserved cleavage and polyadenylation events in mammalian genes. Genome Res. 2018 10; 28(10):1427-1441.
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Zheng D, Wang R, Ding Q, Wang T, Xie B, Wei L, Zhong Z, Tian B. Cellular stress alters 3'UTR landscape through alternative polyadenylation and isoform-specific degradation. Nat Commun. 2018 06 11; 9(1):2268.
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Choi J, Lee K, Ingvarsdottir K, Bonasio R, Saraf A, Florens L, Washburn MP, Tadros S, Green MR, Busino L. Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2. Nat Cell Biol. 2018 05; 20(5):586-596.
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Limoncelli KA, Merrikh CN, Moore MJ. ASC1 and RPS3: new actors in 18S nonfunctional rRNA decay. RNA. 2017 12; 23(12):1946-1960.
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Deveau LM, Massi F. Three Residues Make an Evolutionary Switch for Folding and RNA-Destabilizing Activity in the TTP Family of Proteins. ACS Chem Biol. 2016 Feb 19; 11(2):435-43.
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Uprety P, Chadwick EG, Rainwater-Lovett K, Ziemniak C, Luzuriaga K, Capparelli EV, Yenokyan G, Persaud D. Cell-Associated HIV-1 DNA and RNA Decay Dynamics During Early Combination Antiretroviral Therapy in HIV-1-Infected Infants. Clin Infect Dis. 2015 Dec 15; 61(12):1862-70.
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Momen-Heravi F, Saha B, Kodys K, Catalano D, Satishchandran A, Szabo G. Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis. J Transl Med. 2015 Aug 12; 13:261.
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Singh G, Pratt G, Yeo GW, Moore MJ. The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion. Annu Rev Biochem. 2015; 84:325-54.
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Carpenter S, Ricci EP, Mercier BC, Moore MJ, Fitzgerald KA. Post-transcriptional regulation of gene expression in innate immunity. Nat Rev Immunol. 2014 Jun; 14(6):361-76.
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