Heterotrimeric GTP-Binding Proteins
"Heterotrimeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.
Descriptor ID |
D020962
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MeSH Number(s) |
D08.811.277.040.330.300.200 D12.644.360.360 D12.776.157.325.332 D12.776.476.375 D12.776.543.325
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Concept/Terms |
Heterotrimeric GTP-Binding Proteins- Heterotrimeric GTP-Binding Proteins
- GTP-Binding Proteins, Heterotrimeric
- Heterotrimeric GTP Binding Proteins
- Heterotrimeric G-Proteins
- G-Proteins, Heterotrimeric
- Heterotrimeric G Proteins
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Below are MeSH descriptors whose meaning is more general than "Heterotrimeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Heterotrimeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Heterotrimeric GTP-Binding Proteins" by people in this website by year, and whether "Heterotrimeric GTP-Binding Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterotrimeric GTP-Binding Proteins" by people in Profiles.
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Yang CH, Rumpf S, Xiang Y, Gordon MD, Song W, Jan LY, Jan YN. Control of the postmating behavioral switch in Drosophila females by internal sensory neurons. Neuron. 2009 Feb 26; 61(4):519-26.
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Strickfaden SC, Pryciak PM. Distinct roles for two Galpha-Gbeta interfaces in cell polarity control by a yeast heterotrimeric G protein. Mol Biol Cell. 2008 Jan; 19(1):181-97.
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Winters MJ, Lamson RE, Nakanishi H, Neiman AM, Pryciak PM. A membrane binding domain in the ste5 scaffold synergizes with gbetagamma binding to control localization and signaling in pheromone response. Mol Cell. 2005 Oct 07; 20(1):21-32.
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Nishiguchi KM, Sandberg MA, Gorji N, Berson EL, Dryja TP. Cone cGMP-gated channel mutations and clinical findings in patients with achromatopsia, macular degeneration, and other hereditary cone diseases. Hum Mutat. 2005 Mar; 25(3):248-58.
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Cheng H, Khanna H, Oh EC, Hicks D, Mitton KP, Swaroop A. Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. Hum Mol Genet. 2004 Aug 01; 13(15):1563-75.
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Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res. 2002 Dec 15; 62(24):7203-6.
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Park JG, Bose A, Leszyk J, Czech MP. PYK2 as a mediator of endothelin-1/G alpha 11 signaling to GLUT4 glucose transporters. J Biol Chem. 2001 Dec 21; 276(51):47751-4.
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Dosil M, Schandel KA, Gupta E, Jenness DD, Konopka JB. The C terminus of the Saccharomyces cerevisiae alpha-factor receptor contributes to the formation of preactivation complexes with its cognate G protein. Mol Cell Biol. 2000 Jul; 20(14):5321-9.