Phosphorylation

"Phosphorylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.

Descriptor ID	D010766
MeSH Number(s)	G02.111.665 G02.607.780 G03.796
Concept/Terms	Phosphorylation Phosphorylation Phosphorylations

Below are MeSH descriptors whose meaning is more general than "Phosphorylation".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Phosphorylation [G02.111.665]
Organic Chemistry Phenomena [G02.607]
Phosphorylation [G02.607.780]
Metabolism [G03]
Phosphorylation [G03.796]

Below are MeSH descriptors whose meaning is related to "Phosphorylation".

Below are MeSH descriptors whose meaning is more specific than "Phosphorylation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Phosphorylation" by people in this website by year, and whether "Phosphorylation" was a major or minor topic of these publications.

Bar chart showing 709 publications over 31 distinct years, with a maximum of 44 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	6	6
1996	0	4	4
1997	0	11	11
1998	0	11	11
1999	0	14	14
2000	0	10	10
2001	0	15	15
2002	0	40	40
2003	0	36	36
2004	0	39	39
2005	0	36	36
2006	0	32	32
2007	0	31	31
2008	1	28	29
2009	0	29	29
2010	0	34	34
2011	0	34	34
2012	0	33	33
2013	0	44	44
2014	0	33	33
2015	0	36	36
2016	1	28	29
2017	1	24	25
2018	0	18	18
2019	0	20	20
2020	1	23	24
2021	1	15	16
2022	0	6	6
2023	0	5	5
2024	0	8	8
2025	0	1	1

Below are the most recent publications written about "Phosphorylation" by people in Profiles.

Johnson KM, Marley MG, Drizyte-Miller K, Chen J, Cao H, Mostafa N, Schott MB, McNiven MA, Razidlo GL. Rab32 regulates Golgi structure and cell migration through Protein Kinase A-mediated phosphorylation of Optineurin. Proc Natl Acad Sci U S A. 2025 Apr 29; 122(17):e2502971122.

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Li W, Mei W, Jiang H, Wang J, Li X, Quan L, Diao Y, Ma Y, Fan S, Xie Z, Gong M, Zhu H, Bi D, Zhang F, Ma L, Zhang J, Gao Y, Paschalidis A, Lin H, Liu F, Liu K, Ye M, Zhao Z, Duan Y, Chen Z, Xu Y, Xiao W, Tao S, Zhu L, Li H. Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2. Sci China Life Sci. 2025 Jan; 68(1):189-203.

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Nagesh PT, Cho Y, Zhuang Y, Babuta M, Ortega-Ribera M, Joshi R, Brezani V, Patel A, Datta AA, Brezani V, Hsieh YC, Ramos A, Mehta J, Copeland C, Kanata E, Jiang ZG, Vlachos I, Asara J, Szabo G. In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis. Sci Transl Med. 2024 08 07; 16(759):eadg1915.

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Jablo?ski M, La Spina FA, Schiavi-Ehrenhaus LJ, Mar?n-Briggiler CI, Gomez-Elias MD, Krapf D, Visconti PE, Krapf D, Luque GM, Buffone MG. Dual role of valosin-containing protein (VCP/p97) in mouse sperm during capacitation. Reproduction. 2024 08 01; 168(2).

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Olea-Flores M, Sharma T, Verdejo-Torres O, DiBartolomeo I, Thompson PR, Padilla-Benavides T, Imbalzano AN. Muscle-specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation. FASEB J. 2024 Jun 15; 38(11):e23702.

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Gibbons CH, Levine T, Adler C, Bellaire B, Wang N, Stohl J, Agarwal P, Aldridge GM, Barboi A, Evidente VGH, Galasko D, Geschwind MD, Gonzalez-Duarte A, Gil R, Gudesblatt M, Isaacson SH, Kaufmann H, Khemani P, Kumar R, Lamotte G, Liu AJ, McFarland NR, Miglis M, Reynolds A, Sahagian GA, Saint-Hillaire MH, Schwartzbard JB, Singer W, Soileau MJ, Vernino S, Yerstein O, Freeman R. Skin Biopsy Detection of Phosphorylated a-Synuclein in Patients With Synucleinopathies. JAMA. 2024 04 16; 331(15):1298-1306.

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Zhang G, Zheng C, Ding YH, Mello C. Casein kinase II promotes piRNA production through direct phosphorylation of USTC component TOFU-4. Nat Commun. 2024 Mar 28; 15(1):2727.

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Zhuang Y, Szabo G. Reply: How does bile acid-induced IRF3 phosphorylation mediate cholestatic liver and kidney injury?-More needs to be known. Hepatology. 2024 07 01; 80(1):E2-E3.

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Mohanty G, Sanchez-Cardenas C, Paudel B, Tourzani DA, Salicioni AM, Santi CM, Gervasi MG, Pilsner JR, Darszon A, Visconti PE. Differential role of bovine serum albumin and HCO3- in the regulation of GSK3 alpha during mouse sperm capacitation. Mol Hum Reprod. 2024 Feb 29; 30(3).

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Zhuang Y, Ortega-Ribera M, Thevkar Nagesh P, Joshi R, Huang H, Wang Y, Zivny A, Mehta J, Parikh SM, Szabo G. Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1. Hepatology. 2024 04 01; 79(4):752-767.

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