Intracellular Signaling Peptides and Proteins

"Intracellular Signaling Peptides and Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors.

Descriptor ID	D047908
MeSH Number(s)	D12.644.360 D12.776.476
Concept/Terms	Intracellular Signaling Peptides and Proteins Intracellular Signaling Peptides and Proteins Intracellular Signaling Peptides Intracellular Signaling Peptides Peptides, Intracellular Signaling Signaling Peptides, Intracellular Intracellular Signaling Proteins Intracellular Signaling Proteins Proteins, Intracellular Signaling Signaling Proteins, Intracellular

Below are MeSH descriptors whose meaning is more general than "Intracellular Signaling Peptides and Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]

Below are MeSH descriptors whose meaning is related to "Intracellular Signaling Peptides and Proteins".

Below are MeSH descriptors whose meaning is more specific than "Intracellular Signaling Peptides and Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Intracellular Signaling Peptides and Proteins" by people in this website by year, and whether "Intracellular Signaling Peptides and Proteins" was a major or minor topic of these publications.

Bar chart showing 237 publications over 29 distinct years, with a maximum of 17 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	0	1
1994	0	1	1
1995	0	1	1
1996	0	2	2
1997	0	10	10
1998	0	3	3
1999	2	3	5
2000	0	2	2
2001	0	3	3
2002	3	5	8
2003	3	6	9
2004	2	9	11
2005	4	11	15
2006	6	11	17
2007	9	7	16
2008	5	6	11
2009	7	6	13
2010	8	5	13
2011	7	6	13
2012	5	3	8
2013	4	11	15
2014	4	4	8
2015	7	4	11
2016	6	3	9
2017	3	6	9
2018	6	5	11
2019	1	3	4
2020	3	2	5
2021	1	2	3

Below are the most recent publications written about "Intracellular Signaling Peptides and Proteins" by people in Profiles.

Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nat Neurosci. 2021 11; 24(11):1522-1533.

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Rueda-Carrasco J, Martin-Bermejo MJ, Pereyra G, Mateo MI, Borroto A, Brosseron F, Kummer MP, Schwartz S, López-Atalaya JP, Alarcon B, Esteve P, Heneka MT, Bovolenta P. SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation. EMBO Rep. 2021 11 04; 22(11):e51696.

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Sturgeon SR, Sela DA, Browne EP, Einson J, Rani A, Halabi M, Kania T, Keezer A, Balasubramanian R, Ziegler RG, Schairer C, Kelsey KT, Arcaro KF. Prediagnostic White Blood Cell DNA Methylation and Risk of Breast Cancer in the Prostate Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) Cohort. Cancer Epidemiol Biomarkers Prev. 2021 08; 30(8):1575-1581.

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Li J, Lambright DG, Hsu VW. Coordination of Grp1 recruitment mechanisms by its phosphorylation. Mol Biol Cell. 2020 12 01; 31(25):2816-2825.

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Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, Thompson PR, Fitzgerald KA. Succination inactivates gasdermin D and blocks pyroptosis. Science. 2020 09 25; 369(6511):1633-1637.

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Murtas G, Sacchi S, Kumar MS, Bosco DA, Pollegioni L. Is the primate-specific protein pLG72 affecting SOD1 functionality and superoxide formation? Free Radic Res. 2020 Jun; 54(6):419-430.

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Selkrig J, Li N, Hausmann A, Mangan MSJ, Zietek M, Mateus A, Bobonis J, Sueki A, Imamura H, El Debs B, Sigismondo G, Florea BI, Overkleeft HS, Kopitar-Jerala N, Turk B, Beltrao P, Savitski MM, Latz E, Hardt WD, Krijgsveld J, Typas A. Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection. Nat Microbiol. 2020 09; 5(9):1119-1133.

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Das DK, Bulow U, Diehl WE, Durham ND, Senjobe F, Chandran K, Luban J, Munro JB. Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding. PLoS Biol. 2020 02; 18(2):e3000626.

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Deng M, Guo H, Tam JW, Johnson BM, Brickey WJ, New JS, Lenox A, Shi H, Golenbock DT, Koller BH, McKinnon KP, Beutler B, Ting JP. Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR. J Exp Med. 2019 12 02; 216(12):2838-2853.

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Orning P, Lien E, Fitzgerald KA. Gasdermins and their role in immunity and inflammation. J Exp Med. 2019 11 04; 216(11):2453-2465.

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