Inhibitor of Growth Protein 1
"Inhibitor of Growth Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
| Descriptor ID |
D000076023
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| MeSH Number(s) |
D12.644.360.368 D12.776.476.383 D12.776.624.776.503 D12.776.660.494
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Inhibitor of Growth Protein 1".
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This graph shows the total number of publications written about "Inhibitor of Growth Protein 1" by people in this website by year, and whether "Inhibitor of Growth Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Inhibitor of Growth Protein 1" by people in Profiles.
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Coles AH, Marfella CG, Imbalzano AN, Steinman HA, Garlick DS, Gerstein RM, Jones SN. p37Ing1b regulates B-cell proliferation and cooperates with p53 to suppress diffuse large B-cell lymphomagenesis. Cancer Res. 2008 Nov 01; 68(21):8705-14.
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Coles AH, Liang H, Zhu Z, Marfella CG, Kang J, Imbalzano AN, Jones SN. Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis. Cancer Res. 2007 Mar 01; 67(5):2054-61.