 Proto-Oncogene Proteins c-akt
"Proto-Oncogene Proteins c-akt" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
| Descriptor ID |
D051057
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| MeSH Number(s) |
D08.811.913.696.620.682.700.755 D12.776.476.565 D12.776.624.664.700.168
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| Concept/Terms |
Proto-Oncogene Proteins c-akt- Proto-Oncogene Proteins c-akt
- Proto Oncogene Proteins c akt
- c-akt, Proto-Oncogene Proteins
- c-akt Protein
- c-akt Proto-Oncogene Protein
- Protein, c-akt Proto-Oncogene
- Proto-Oncogene Protein, c-akt
- c akt Proto Oncogene Protein
- Protein Kinase B
- Protein-Serine-Threonine Kinase (Rac)
- Proto-Oncogene Protein RAC
- Proto Oncogene Protein RAC
- RAC, Proto-Oncogene Protein
- Rac Protein Kinase
- RAC-PK Protein
- RAC PK Protein
- Related to A and C-Protein
- Related to A and C Protein
- akt Proto-Oncogene Protein
- Protein, akt Proto-Oncogene
- Proto-Oncogene Protein, akt
- akt Proto Oncogene Protein
- Proto-Oncogene Protein Akt
- Akt, Proto-Oncogene Protein
- Proto Oncogene Protein Akt
Proto-Oncogene Proteins c-akt3- Proto-Oncogene Proteins c-akt3
- Proteins c-akt3, Proto-Oncogene
- Proto Oncogene Proteins c akt3
- c-akt3, Proto-Oncogene Proteins
- AKT3 Protein Kinase
- Protein Kinase B gamma
- Akt-gamma Protein
- Akt gamma Protein
Proto-Oncogene Proteins c-akt1- Proto-Oncogene Proteins c-akt1
- Proteins c-akt1, Proto-Oncogene
- Proto Oncogene Proteins c akt1
- c-akt1, Proto-Oncogene Proteins
- Rac-PK alpha Protein
- Rac PK alpha Protein
- alpha Protein, Rac-PK
- Protein Kinase B alpha
- Akt-alpha Protein
- Akt alpha Protein
- AKT1 Protein Kinase
Proto-Oncogene Proteins c-akt2- Proto-Oncogene Proteins c-akt2
- Proteins c-akt2, Proto-Oncogene
- Proto Oncogene Proteins c akt2
- c-akt2, Proto-Oncogene Proteins
- Rac-PK beta Protein
- Rac PK beta Protein
- Protein Kinase B beta
- Akt-beta Protein
- Akt beta Protein
- AKT2 Protein Kinase
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-akt".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-akt".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-akt" by people in this website by year, and whether "Proto-Oncogene Proteins c-akt" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 2 | 2 | | 2005 | 1 | 11 | 12 | | 2006 | 4 | 3 | 7 | | 2007 | 1 | 7 | 8 | | 2008 | 3 | 8 | 11 | | 2009 | 3 | 6 | 9 | | 2010 | 4 | 5 | 9 | | 2011 | 5 | 6 | 11 | | 2012 | 1 | 5 | 6 | | 2013 | 4 | 6 | 10 | | 2014 | 5 | 7 | 12 | | 2015 | 0 | 5 | 5 | | 2016 | 0 | 5 | 5 | | 2017 | 0 | 2 | 2 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-akt" by people in Profiles.
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Martinez Calejman C, Trefely S, Entwisle SW, Luciano A, Jung SM, Hsiao W, Torres A, Hung CM, Li H, Snyder NW, Villén J, Wellen KE, Guertin DA. mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis. Nat Commun. 2020 Jan 29; 11(1):575.
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Wang T, Xie C, Yu P, Fang F, Zhu J, Cheng J, Gu A, Wang J, Xiao H. Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity. Sci Rep. 2017 08 08; 7(1):7497.
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Ciccarese C, Massari F, Iacovelli R, Fiorentino M, Montironi R, Di Nunno V, Giunchi F, Brunelli M, Tortora G. Prostate cancer heterogeneity: Discovering novel molecular targets for therapy. Cancer Treat Rev. 2017 Mar; 54:68-73.
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Ciccarese C, Brunelli M, Montironi R, Fiorentino M, Iacovelli R, Heng D, Tortora G, Massari F. The prospect of precision therapy for renal cell carcinoma. Cancer Treat Rev. 2016 Sep; 49:37-44.
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Tang Y, Wallace M, Sanchez-Gurmaches J, Hsiao WY, Li H, Lee PL, Vernia S, Metallo CM, Guertin DA. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism. Nat Commun. 2016 Apr 21; 7:11365.
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Myers AP, Filiaci VL, Zhang Y, Pearl M, Behbakht K, Makker V, Hanjani P, Zweizig S, Burke JJ, Downey G, Leslie KK, Van Hummelen P, Birrer MJ, Fleming GF. Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study. Gynecol Oncol. 2016 Apr; 141(1):43-8.
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Massari F, Ciccarese C, Santoni M, Iacovelli R, Mazzucchelli R, Piva F, Scarpelli M, Berardi R, Tortora G, Lopez-Beltran A, Cheng L, Montironi R. Metabolic phenotype of bladder cancer. Cancer Treat Rev. 2016 Apr; 45:46-57.
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Senol-Cosar O, Flach RJ, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, Hardy OT, Noh HL, Kim JK, Wabitsch M, Scherer PE, Czech MP. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion. Nat Commun. 2016 Feb 16; 7:10686.
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Ruscetti M, Dadashian EL, Guo W, Quach B, Mulholland DJ, Park JW, Tran LM, Kobayashi N, Bianchi-Frias D, Xing Y, Nelson PS, Wu H. HDAC inhibition impedes epithelial-mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer. Oncogene. 2016 07 21; 35(29):3781-95.
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Wilson JE, Petrucelli AS, Chen L, Koblansky AA, Truax AD, Oyama Y, Rogers AB, Brickey WJ, Wang Y, Schneider M, Mühlbauer M, Chou WC, Barker BR, Jobin C, Allbritton NL, Ramsden DA, Davis BK, Ting JP. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nat Med. 2015 Aug; 21(8):906-13.
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