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David Guertin

Concepts (351)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Adipose Tissue, Brown
11
2024
119
5.460
Why?
Proto-Oncogene Proteins c-akt
17
2022
204
3.400
Why?
Mechanistic Target of Rapamycin Complex 2
9
2020
17
3.070
Why?
Adipocytes
14
2022
269
2.870
Why?
TOR Serine-Threonine Kinases
19
2022
121
2.810
Why?
Adipose Tissue, White
10
2022
87
2.640
Why?
Adipocytes, Brown
8
2023
45
2.370
Why?
Adipogenesis
9
2019
79
2.240
Why?
Lipogenesis
7
2020
68
2.120
Why?
Thermogenesis
8
2024
121
2.120
Why?
Obesity
11
2023
1232
2.040
Why?
ATP Citrate (pro-S)-Lyase
3
2024
17
1.730
Why?
Glutamine
2
2024
46
1.690
Why?
Protein Kinases
10
2009
152
1.600
Why?
Multiprotein Complexes
10
2016
155
1.600
Why?
Insulin
9
2022
687
1.520
Why?
Rapamycin-Insensitive Companion of mTOR Protein
9
2022
11
1.500
Why?
Signal Transduction
26
2022
3027
1.310
Why?
Transcription Factors
10
2017
1512
1.250
Why?
Diabetes Mellitus, Type 2
4
2022
692
1.240
Why?
Animals
48
2024
20640
1.170
Why?
Carrier Proteins
8
2020
706
1.140
Why?
Adipose Tissue
6
2024
296
1.130
Why?
Subcutaneous Fat
2
2020
47
1.130
Why?
Mice
32
2024
10834
1.090
Why?
Glucose
7
2023
470
1.090
Why?
Myogenic Regulatory Factor 5
4
2014
16
1.070
Why?
Neoplasms
5
2023
1351
0.980
Why?
Insulin Resistance
7
2019
410
0.970
Why?
Mechanistic Target of Rapamycin Complex 1
9
2017
51
0.940
Why?
Cell Lineage
8
2019
268
0.920
Why?
Nuclear Proteins
5
2019
777
0.910
Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
4
2019
39
0.870
Why?
PTEN Phosphohydrolase
4
2012
84
0.860
Why?
Adipocytes, White
2
2015
27
0.860
Why?
Metabolic Diseases
1
2024
57
0.850
Why?
Lipid Metabolism
4
2020
221
0.840
Why?
Phosphatidylinositol 3-Kinases
5
2012
171
0.820
Why?
Acetyl Coenzyme A
1
2023
24
0.810
Why?
ADP-Ribosylation Factor 1
1
2022
5
0.790
Why?
Stress, Physiological
1
2024
193
0.790
Why?
Protein Interaction Maps
1
2022
35
0.780
Why?
Cold Temperature
2
2021
51
0.740
Why?
Isotope Labeling
1
2021
70
0.730
Why?
Energy Metabolism
5
2022
379
0.680
Why?
Forkhead Box Protein O1
2
2019
18
0.670
Why?
Cell Growth Processes
2
2012
37
0.660
Why?
Fatty Acids
4
2024
200
0.650
Why?
Second Messenger Systems
1
2019
27
0.650
Why?
Cell Division
5
2006
451
0.650
Why?
Sirtuins
1
2019
26
0.630
Why?
Protein Kinase Inhibitors
2
2012
187
0.630
Why?
Lipolysis
1
2019
47
0.620
Why?
Muscle Development
2
2019
54
0.620
Why?
Sirtuin 1
1
2018
27
0.610
Why?
Oncogenes
1
2019
68
0.600
Why?
Gastrointestinal Transit
1
2018
6
0.600
Why?
Phosphorylation
10
2022
938
0.580
Why?
Sirolimus
6
2012
92
0.570
Why?
Gene Knockout Techniques
3
2020
95
0.560
Why?
Trans-Activators
2
2012
312
0.560
Why?
Humans
35
2025
62967
0.540
Why?
Lipodystrophy
1
2017
11
0.540
Why?
Mice, Inbred C57BL
10
2021
3395
0.540
Why?
Prostatic Neoplasms
2
2012
404
0.520
Why?
Cell Cycle Proteins
4
2004
396
0.500
Why?
Protein Subunits
1
2016
166
0.490
Why?
Cell Differentiation
5
2019
1351
0.480
Why?
Homologous Recombination
1
2015
28
0.470
Why?
rab1 GTP-Binding Proteins
1
2014
6
0.470
Why?
Integrases
1
2015
37
0.460
Why?
Liver
3
2016
847
0.450
Why?
Homeodomain Proteins
1
2015
267
0.420
Why?
Citric Acid Cycle
2
2024
28
0.410
Why?
Schizosaccharomyces pombe Proteins
3
2004
74
0.410
Why?
Intracellular Signaling Peptides and Proteins
2
2016
336
0.400
Why?
Schizosaccharomyces
4
2004
105
0.390
Why?
Drosophila Proteins
5
2011
691
0.380
Why?
Mice, Knockout
7
2019
2109
0.370
Why?
Colorectal Neoplasms
1
2014
280
0.370
Why?
Cell Survival
1
2012
573
0.350
Why?
Protein Tyrosine Phosphatases
2
2001
59
0.340
Why?
Autophagy
1
2012
225
0.340
Why?
Fatty Acid Synthases
2
2020
24
0.320
Why?
Phosphotransferases (Alcohol Group Acceptor)
1
2009
48
0.300
Why?
Antibiotics, Antineoplastic
2
2006
36
0.300
Why?
Muscle, Skeletal
4
2023
739
0.300
Why?
Proteins
9
2012
751
0.300
Why?
Saccharomyces cerevisiae Proteins
3
2004
442
0.300
Why?
Protein Kinase C-alpha
2
2006
16
0.280
Why?
HEK293 Cells
2
2020
618
0.270
Why?
Forkhead Transcription Factors
2
2011
129
0.270
Why?
Ribosomal Protein S6 Kinases
1
2006
10
0.270
Why?
Drosophila
3
2006
432
0.260
Why?
Genes, Developmental
1
2006
5
0.260
Why?
Gene Expression Regulation
4
2017
1618
0.240
Why?
Male
13
2023
29619
0.240
Why?
Nucleotides
1
2025
48
0.240
Why?
Models, Biological
5
2016
1183
0.240
Why?
Metabolic Networks and Pathways
2
2023
87
0.240
Why?
Spindle Apparatus
2
2002
123
0.230
Why?
Aneuploidy
1
2025
42
0.230
Why?
Gene Expression
2
2020
838
0.220
Why?
Glycolysis
2
2021
58
0.220
Why?
PPAR gamma
3
2020
76
0.220
Why?
Mice, Transgenic
2
2019
1273
0.210
Why?
Disease Models, Animal
4
2023
2181
0.210
Why?
Mitosis
2
2002
218
0.210
Why?
Body Fat Distribution
2
2013
13
0.210
Why?
Genes, cdc
1
2002
15
0.200
Why?
Adipokines
1
2022
30
0.200
Why?
Protein Interaction Mapping
1
2022
68
0.190
Why?
RNA Interference
6
2011
619
0.190
Why?
Genomics
2
2024
369
0.190
Why?
DNA Damage
1
2024
285
0.190
Why?
Phosphatidylglycerols
1
2021
12
0.190
Why?
Metabolomics
1
2022
54
0.180
Why?
Cells, Cultured
5
2014
2158
0.180
Why?
Metabolome
1
2021
30
0.180
Why?
Cell Transformation, Neoplastic
3
2012
207
0.180
Why?
Luminescent Proteins
3
2012
128
0.180
Why?
Gene Targeting
2
2015
78
0.180
Why?
Protein Binding
5
2009
1607
0.180
Why?
Female
10
2025
32618
0.180
Why?
Diet, High-Fat
3
2019
174
0.170
Why?
Oxidation-Reduction
1
2021
325
0.170
Why?
Homeostasis
3
2019
368
0.170
Why?
Amino Acids
1
2021
146
0.170
Why?
Acetate-CoA Ligase
1
2020
1
0.170
Why?
Response Elements
1
2020
44
0.160
Why?
Adult
4
2023
16691
0.160
Why?
Glucose Transporter Type 4
1
2020
60
0.160
Why?
Gene Expression Profiling
4
2011
770
0.160
Why?
Transcriptome
2
2021
386
0.160
Why?
Neural Crest
1
2019
27
0.160
Why?
HeLa Cells
2
2019
533
0.160
Why?
Protein Methyltransferases
1
2019
14
0.150
Why?
Dietary Carbohydrates
1
2019
61
0.150
Why?
Proteome
1
2020
149
0.150
Why?
Neural Stem Cells
1
2019
48
0.150
Why?
Histone-Lysine N-Methyltransferase
1
2019
32
0.150
Why?
Amino Acids, Branched-Chain
1
2018
13
0.150
Why?
Tumor Suppressor Proteins
2
2012
198
0.150
Why?
Methylation
1
2019
128
0.150
Why?
Neurogenesis
1
2019
63
0.150
Why?
Stromal Cells
1
2018
67
0.150
Why?
Proteomics
1
2020
284
0.140
Why?
Uncoupling Protein 1
1
2017
50
0.140
Why?
Carcinogenesis
1
2019
130
0.140
Why?
Gene Deletion
2
2016
308
0.140
Why?
Adaptor Proteins, Signal Transducing
4
2013
429
0.130
Why?
Diabetes Mellitus, Experimental
1
2017
199
0.130
Why?
Histones
1
2020
482
0.130
Why?
Epigenesis, Genetic
1
2020
384
0.130
Why?
Receptors, Immunologic
1
2017
177
0.130
Why?
Flow Cytometry
2
2012
670
0.120
Why?
Protein Structure, Tertiary
4
2015
670
0.120
Why?
Gene Editing
1
2020
310
0.120
Why?
Tuberculosis
1
2019
294
0.120
Why?
Mutation
4
2006
2601
0.120
Why?
Gene Expression Regulation, Developmental
1
2019
640
0.120
Why?
Organ Specificity
1
2016
193
0.120
Why?
Inflammation
2
2019
1142
0.120
Why?
Cytoskeleton
2
2006
138
0.120
Why?
Sterol Regulatory Element Binding Protein 1
2
2011
22
0.110
Why?
Up-Regulation
2
2006
375
0.110
Why?
Epithelial Cells
2
2025
390
0.110
Why?
Bone Morphogenetic Protein 7
1
2014
16
0.110
Why?
MyoD Protein
1
2014
45
0.110
Why?
Receptor, Insulin
1
2014
50
0.110
Why?
Diet
1
2017
523
0.110
Why?
Stem Cells
1
2016
259
0.110
Why?
Cell Proliferation
3
2013
981
0.110
Why?
Th2 Cells
1
2013
98
0.110
Why?
Proto-Oncogene Proteins
2
2005
324
0.100
Why?
Receptors, Adrenergic, beta-3
1
2012
6
0.100
Why?
Receptors, Cell Surface
1
2015
431
0.100
Why?
Lipomatosis
1
2012
8
0.100
Why?
Histological Techniques
1
2012
18
0.100
Why?
Leukemia
1
2012
62
0.100
Why?
Hematopoiesis
1
2012
124
0.100
Why?
Muscle Cells
1
2011
28
0.090
Why?
Real-Time Polymerase Chain Reaction
1
2012
208
0.090
Why?
Sterol Regulatory Element Binding Protein 2
1
2011
6
0.090
Why?
Sarcoma
1
2011
36
0.090
Why?
Cell Separation
1
2011
147
0.090
Why?
Ribosomal Protein S6
1
2011
1
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2012
545
0.090
Why?
Lymphocyte Activation
1
2013
759
0.090
Why?
Longevity
1
2012
113
0.090
Why?
Drug Discovery
1
2012
95
0.090
Why?
Membrane Proteins
1
2017
894
0.090
Why?
Antineoplastic Agents
2
2024
662
0.080
Why?
Adenosine Triphosphate
1
2012
292
0.080
Why?
Regulatory-Associated Protein of mTOR
4
2013
7
0.080
Why?
Tacrolimus Binding Protein 1A
1
2009
2
0.080
Why?
Cell Line
3
2015
2039
0.080
Why?
Everolimus
1
2009
22
0.080
Why?
Microarray Analysis
2
2011
65
0.080
Why?
Green Fluorescent Proteins
2
2001
364
0.080
Why?
Mice, Obese
2
2019
80
0.080
Why?
T-Lymphocytes
1
2013
1005
0.080
Why?
Neoplasm Transplantation
1
2009
165
0.080
Why?
Fluorescent Antibody Technique
3
2011
233
0.080
Why?
Recombinant Proteins
1
2011
701
0.070
Why?
Mice, Nude
1
2009
272
0.070
Why?
Prostate
1
2009
85
0.070
Why?
Transplantation, Heterologous
1
2009
229
0.070
Why?
Phenotype
2
2009
1198
0.070
Why?
3T3 Cells
2
2018
110
0.070
Why?
Drosophila melanogaster
3
2011
490
0.070
Why?
Aged, 80 and over
1
2017
5424
0.070
Why?
Young Adult
1
2017
4660
0.070
Why?
Forkhead Box Protein O3
1
2006
9
0.070
Why?
Fetal Viability
1
2006
4
0.070
Why?
Fibroblasts
1
2009
392
0.070
Why?
Mice, Inbred BALB C
1
2009
894
0.070
Why?
Immunosuppressive Agents
1
2009
377
0.070
Why?
Glycogen Synthase Kinase 3 beta
1
2006
32
0.070
Why?
Fetal Development
1
2006
17
0.070
Why?
Glycogen Synthase Kinase 3
1
2006
45
0.070
Why?
Bacterial Proteins
1
2012
769
0.060
Why?
Cell Enlargement
1
2006
9
0.060
Why?
Middle Aged
3
2019
17428
0.060
Why?
Embryo, Mammalian
1
2006
157
0.060
Why?
Precipitin Tests
2
2004
77
0.060
Why?
Genes, Tumor Suppressor
1
2005
72
0.060
Why?
Oxidative Phosphorylation
1
2025
41
0.060
Why?
Down-Regulation
1
2006
319
0.060
Why?
DNA Copy Number Variations
1
2025
72
0.060
Why?
Electrophoresis, Polyacrylamide Gel
2
2004
182
0.060
Why?
Mammary Glands, Human
1
2025
56
0.060
Why?
Immunoblotting
2
2004
204
0.060
Why?
Blotting, Western
2
2011
611
0.060
Why?
Pyrimidines
1
2025
135
0.060
Why?
Cell Cycle
3
2013
393
0.060
Why?
Transcription, Genetic
2
2015
876
0.060
Why?
Amino Acid Sequence
3
2004
1595
0.050
Why?
Ribosomes
1
2006
163
0.050
Why?
Molecular Sequence Data
3
2004
1997
0.050
Why?
Cell Line, Tumor
2
2024
1460
0.050
Why?
Adrenergic Agents
1
2022
15
0.050
Why?
Phosphoproteins
1
2004
220
0.050
Why?
Cell Death
1
2024
284
0.050
Why?
Plant Cells
1
2002
11
0.050
Why?
Actomyosin
1
2002
21
0.050
Why?
Microtubule-Associated Proteins
1
2002
115
0.050
Why?
Yeasts
1
2002
51
0.050
Why?
Carbon Isotopes
1
2022
17
0.050
Why?
Cyclin-Dependent Kinases
1
2002
46
0.050
Why?
Eukaryotic Cells
1
2002
57
0.050
Why?
Tumor Suppressor Protein p53
1
2024
304
0.050
Why?
Aged
1
2017
14299
0.050
Why?
Phosphotransferases
1
2001
23
0.050
Why?
Microtubules
1
2002
209
0.050
Why?
RNA
1
2004
422
0.040
Why?
Catalysis
1
2001
161
0.040
Why?
Plasmids
1
2001
292
0.040
Why?
Catalytic Domain
1
2001
198
0.040
Why?
Structure-Activity Relationship
1
2001
369
0.040
Why?
Mass Spectrometry
1
2022
305
0.040
Why?
Gene Ontology
1
2020
38
0.040
Why?
Temperature
1
2001
309
0.040
Why?
Tubulin
1
2000
73
0.040
Why?
Chromatography, Liquid
1
2020
131
0.040
Why?
Mutagenesis
1
2000
133
0.040
Why?
Alleles
1
2001
450
0.040
Why?
Microscopy, Fluorescence
1
2001
400
0.040
Why?
Neural Tube
1
2019
12
0.040
Why?
Twist-Related Protein 1
1
2019
11
0.040
Why?
Recombinant Fusion Proteins
1
2001
495
0.040
Why?
Sequence Homology, Amino Acid
1
2000
364
0.040
Why?
Cloning, Molecular
1
2000
384
0.040
Why?
Tandem Mass Spectrometry
1
2020
146
0.040
Why?
Acetylation
1
2019
121
0.040
Why?
Carnitine O-Acetyltransferase
1
2018
1
0.040
Why?
Neuroglia
1
2019
79
0.040
Why?
Mice, Mutant Strains
1
2019
302
0.040
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2019
125
0.040
Why?
Apoptosis
1
2024
1071
0.040
Why?
Protein Biosynthesis
1
2001
317
0.040
Why?
Lentivirus
1
2018
66
0.040
Why?
Single-Cell Analysis
1
2019
114
0.040
Why?
Cytosol
1
2018
180
0.040
Why?
Hypoxia
1
2018
113
0.030
Why?
DNA-Binding Proteins
1
2004
1184
0.030
Why?
RNA, Small Interfering
2
2018
908
0.030
Why?
Ubiquitin-Conjugating Enzymes
1
2016
24
0.030
Why?
3T3-L1 Cells
1
2017
90
0.030
Why?
NIH 3T3 Cells
1
2017
99
0.030
Why?
Nerve Tissue Proteins
1
2019
424
0.030
Why?
Mitochondria
1
2020
370
0.030
Why?
Bone Morphogenetic Proteins
1
2017
62
0.030
Why?
Ubiquitination
1
2016
111
0.030
Why?
Gene Knockdown Techniques
1
2017
201
0.030
Why?
Neovascularization, Physiologic
1
2017
104
0.030
Why?
Breast Neoplasms
1
2025
1195
0.030
Why?
CCAAT-Enhancer-Binding Protein-alpha
1
2015
14
0.030
Why?
CCAAT-Enhancer-Binding Protein-beta
1
2015
21
0.030
Why?
RNA Polymerase II
1
2015
81
0.030
Why?
Mycobacterium tuberculosis
1
2019
405
0.030
Why?
CRISPR-Cas Systems
1
2018
350
0.030
Why?
Enzyme Activation
2
2005
381
0.030
Why?
Sequence Alignment
2
2004
300
0.030
Why?
Neurons
1
2019
920
0.030
Why?
Hematopoietic Stem Cell Mobilization
1
2012
15
0.020
Why?
Gene Expression Regulation, Leukemic
1
2012
51
0.020
Why?
Time Factors
1
2000
3755
0.020
Why?
Gluconeogenesis
1
2012
15
0.020
Why?
Glucose Clamp Technique
1
2012
58
0.020
Why?
Muscle Neoplasms
1
2011
9
0.020
Why?
Aurothioglucose
1
2011
2
0.020
Why?
Hepatocyte Nuclear Factor 3-beta
1
2011
5
0.020
Why?
Phosphatidate Phosphatase
1
2011
1
0.020
Why?
ras Proteins
1
2011
77
0.020
Why?
Biomarkers
1
2017
1389
0.020
Why?
Survival Analysis
1
2012
580
0.020
Why?
Muscle Fibers, Skeletal
1
2011
93
0.020
Why?
Hematopoietic Stem Cells
1
2012
285
0.020
Why?
Chromatin
1
2015
619
0.020
Why?
Molecular Targeted Therapy
1
2011
129
0.020
Why?
Triglycerides
1
2011
244
0.020
Why?
Cytokines
1
2013
934
0.020
Why?
Immunohistochemistry
1
2011
892
0.020
Why?
Gene Regulatory Networks
1
2011
159
0.020
Why?
Hematopoietic Stem Cell Transplantation
1
2012
350
0.020
Why?
Antirheumatic Agents
1
2011
220
0.020
Why?
Gene Expression Regulation, Neoplastic
1
2011
521
0.020
Why?
Genome
1
2011
277
0.020
Why?
Biomarkers, Tumor
1
2011
505
0.020
Why?
Rats
1
2011
1981
0.020
Why?
Models, Genetic
1
2006
260
0.020
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2005
4
0.010
Why?
Immunoprecipitation
1
2005
126
0.010
Why?
Gene Components
1
2004
5
0.010
Why?
Serine
1
2005
91
0.010
Why?
Dose-Response Relationship, Drug
1
2006
865
0.010
Why?
Equipment Failure Analysis
1
2004
75
0.010
Why?
Conserved Sequence
1
2004
174
0.010
Why?
Protein Kinase C
1
2004
103
0.010
Why?
DNA Primers
1
2004
293
0.010
Why?
Macromolecular Substances
1
2004
160
0.010
Why?
Genetic Testing
1
2004
131
0.010
Why?
Hydrophobic and Hydrophilic Interactions
1
2005
260
0.010
Why?
Equipment Design
1
2004
348
0.010
Why?
Software
1
2006
384
0.010
Why?
Actins
1
2004
259
0.010
Why?
Sequence Analysis, DNA
1
2004
413
0.010
Why?
Image Processing, Computer-Assisted
1
2006
667
0.010
Why?
Transfection
1
2004
692
0.010
Why?
Reproducibility of Results
1
2006
1644
0.010
Why?
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