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David Guertin

Concepts (351)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Adipose Tissue, Brown
11
2024
118
5.360
Why?
Proto-Oncogene Proteins c-akt
17
2022
207
3.330
Why?
Mechanistic Target of Rapamycin Complex 2
9
2020
17
3.000
Why?
Adipocytes
14
2022
268
2.820
Why?
TOR Serine-Threonine Kinases
19
2022
122
2.750
Why?
Adipose Tissue, White
10
2022
87
2.580
Why?
Adipocytes, Brown
8
2023
45
2.320
Why?
Adipogenesis
9
2019
79
2.200
Why?
Lipogenesis
7
2020
68
2.080
Why?
Thermogenesis
8
2024
121
2.070
Why?
Obesity
11
2023
1235
2.010
Why?
ATP Citrate (pro-S)-Lyase
3
2024
17
1.690
Why?
Glutamine
2
2024
47
1.660
Why?
Protein Kinases
10
2009
152
1.570
Why?
Multiprotein Complexes
10
2016
154
1.570
Why?
Insulin
9
2022
686
1.500
Why?
Rapamycin-Insensitive Companion of mTOR Protein
9
2022
11
1.470
Why?
Signal Transduction
26
2022
3035
1.290
Why?
Transcription Factors
10
2017
1513
1.230
Why?
Diabetes Mellitus, Type 2
4
2022
697
1.220
Why?
Animals
48
2024
20663
1.160
Why?
Carrier Proteins
8
2020
707
1.130
Why?
Adipose Tissue
6
2024
295
1.110
Why?
Subcutaneous Fat
2
2020
47
1.100
Why?
Mice
32
2024
10845
1.070
Why?
Glucose
7
2023
467
1.070
Why?
Myogenic Regulatory Factor 5
4
2014
16
1.040
Why?
Neoplasms
5
2023
1364
0.960
Why?
Insulin Resistance
7
2019
412
0.950
Why?
Mechanistic Target of Rapamycin Complex 1
9
2017
53
0.920
Why?
Cell Lineage
8
2019
270
0.900
Why?
Nuclear Proteins
5
2019
778
0.890
Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
4
2019
39
0.850
Why?
PTEN Phosphohydrolase
4
2012
84
0.850
Why?
Adipocytes, White
2
2015
27
0.840
Why?
Metabolic Diseases
1
2024
58
0.840
Why?
Lipid Metabolism
4
2020
219
0.830
Why?
Phosphatidylinositol 3-Kinases
5
2012
171
0.800
Why?
Acetyl Coenzyme A
1
2023
24
0.790
Why?
Stress, Physiological
1
2024
191
0.780
Why?
ADP-Ribosylation Factor 1
1
2022
5
0.780
Why?
Protein Interaction Maps
1
2022
35
0.770
Why?
Cold Temperature
2
2021
51
0.720
Why?
Isotope Labeling
1
2021
70
0.710
Why?
Energy Metabolism
5
2022
379
0.670
Why?
Forkhead Box Protein O1
2
2019
17
0.650
Why?
Cell Growth Processes
2
2012
36
0.650
Why?
Fatty Acids
4
2024
200
0.640
Why?
Second Messenger Systems
1
2019
27
0.640
Why?
Cell Division
5
2006
450
0.630
Why?
Sirtuins
1
2019
26
0.620
Why?
Protein Kinase Inhibitors
2
2012
188
0.610
Why?
Lipolysis
1
2019
46
0.610
Why?
Muscle Development
2
2019
54
0.610
Why?
Sirtuin 1
1
2018
26
0.590
Why?
Oncogenes
1
2019
68
0.590
Why?
Gastrointestinal Transit
1
2018
6
0.580
Why?
Phosphorylation
10
2022
936
0.570
Why?
Sirolimus
6
2012
93
0.560
Why?
Gene Knockout Techniques
3
2020
95
0.550
Why?
Trans-Activators
2
2012
311
0.550
Why?
Humans
35
2025
63449
0.540
Why?
Mice, Inbred C57BL
10
2021
3396
0.530
Why?
Lipodystrophy
1
2017
11
0.530
Why?
Prostatic Neoplasms
2
2012
418
0.510
Why?
Cell Cycle Proteins
4
2004
396
0.490
Why?
Cell Differentiation
5
2019
1353
0.480
Why?
Protein Subunits
1
2016
166
0.480
Why?
Homologous Recombination
1
2015
28
0.460
Why?
rab1 GTP-Binding Proteins
1
2014
6
0.460
Why?
Integrases
1
2015
37
0.450
Why?
Liver
3
2016
855
0.440
Why?
Homeodomain Proteins
1
2015
268
0.410
Why?
Citric Acid Cycle
2
2024
29
0.400
Why?
Schizosaccharomyces pombe Proteins
3
2004
74
0.400
Why?
Intracellular Signaling Peptides and Proteins
2
2016
337
0.390
Why?
Schizosaccharomyces
4
2004
105
0.390
Why?
Drosophila Proteins
5
2011
688
0.370
Why?
Mice, Knockout
7
2019
2109
0.370
Why?
Colorectal Neoplasms
1
2014
276
0.360
Why?
Cell Survival
1
2012
575
0.340
Why?
Protein Tyrosine Phosphatases
2
2001
59
0.340
Why?
Autophagy
1
2012
225
0.330
Why?
Fatty Acid Synthases
2
2020
24
0.310
Why?
Phosphotransferases (Alcohol Group Acceptor)
1
2009
46
0.300
Why?
Antibiotics, Antineoplastic
2
2006
36
0.300
Why?
Muscle, Skeletal
4
2023
741
0.300
Why?
Proteins
9
2012
750
0.290
Why?
Saccharomyces cerevisiae Proteins
3
2004
445
0.290
Why?
Protein Kinase C-alpha
2
2006
16
0.280
Why?
Forkhead Transcription Factors
2
2011
128
0.270
Why?
HEK293 Cells
2
2020
622
0.270
Why?
Ribosomal Protein S6 Kinases
1
2006
10
0.260
Why?
Drosophila
3
2006
433
0.260
Why?
Genes, Developmental
1
2006
5
0.250
Why?
Gene Expression Regulation
4
2017
1617
0.240
Why?
Male
13
2023
29893
0.240
Why?
Models, Biological
5
2016
1180
0.230
Why?
Metabolic Networks and Pathways
2
2023
86
0.230
Why?
Nucleotides
1
2025
49
0.230
Why?
Spindle Apparatus
2
2002
124
0.230
Why?
Aneuploidy
1
2025
42
0.230
Why?
Gene Expression
2
2020
840
0.220
Why?
Glycolysis
2
2021
56
0.220
Why?
PPAR gamma
3
2020
76
0.220
Why?
Disease Models, Animal
4
2023
2187
0.210
Why?
Mice, Transgenic
2
2019
1277
0.210
Why?
Mitosis
2
2002
218
0.210
Why?
Body Fat Distribution
2
2013
14
0.200
Why?
Genes, cdc
1
2002
15
0.200
Why?
Adipokines
1
2022
30
0.200
Why?
RNA Interference
6
2011
618
0.190
Why?
Protein Interaction Mapping
1
2022
68
0.190
Why?
Genomics
2
2024
370
0.190
Why?
DNA Damage
1
2024
287
0.190
Why?
Phosphatidylglycerols
1
2021
12
0.180
Why?
Metabolomics
1
2022
52
0.180
Why?
Cells, Cultured
5
2014
2157
0.180
Why?
Cell Transformation, Neoplastic
3
2012
206
0.180
Why?
Metabolome
1
2021
31
0.180
Why?
Luminescent Proteins
3
2012
128
0.180
Why?
Gene Targeting
2
2015
77
0.180
Why?
Protein Binding
5
2009
1603
0.170
Why?
Female
10
2025
32883
0.170
Why?
Diet, High-Fat
3
2019
175
0.170
Why?
Oxidation-Reduction
1
2021
326
0.170
Why?
Homeostasis
3
2019
368
0.170
Why?
Amino Acids
1
2021
147
0.170
Why?
Acetate-CoA Ligase
1
2020
1
0.160
Why?
Adult
4
2023
16826
0.160
Why?
Response Elements
1
2020
44
0.160
Why?
Glucose Transporter Type 4
1
2020
60
0.160
Why?
Gene Expression Profiling
4
2011
770
0.160
Why?
Transcriptome
2
2021
387
0.160
Why?
Neural Crest
1
2019
27
0.150
Why?
HeLa Cells
2
2019
536
0.150
Why?
Protein Methyltransferases
1
2019
14
0.150
Why?
Dietary Carbohydrates
1
2019
61
0.150
Why?
Proteome
1
2020
150
0.150
Why?
Neural Stem Cells
1
2019
48
0.150
Why?
Histone-Lysine N-Methyltransferase
1
2019
32
0.150
Why?
Amino Acids, Branched-Chain
1
2018
13
0.150
Why?
Tumor Suppressor Proteins
2
2012
198
0.150
Why?
Methylation
1
2019
129
0.150
Why?
Neurogenesis
1
2019
64
0.150
Why?
Stromal Cells
1
2018
68
0.140
Why?
Proteomics
1
2020
283
0.140
Why?
Uncoupling Protein 1
1
2017
49
0.140
Why?
Carcinogenesis
1
2019
130
0.140
Why?
Gene Deletion
2
2016
309
0.140
Why?
Adaptor Proteins, Signal Transducing
4
2013
429
0.130
Why?
Diabetes Mellitus, Experimental
1
2017
199
0.130
Why?
Epigenesis, Genetic
1
2020
385
0.130
Why?
Histones
1
2020
481
0.130
Why?
Receptors, Immunologic
1
2017
177
0.120
Why?
Flow Cytometry
2
2012
664
0.120
Why?
Protein Structure, Tertiary
4
2015
673
0.120
Why?
Tuberculosis
1
2019
295
0.120
Why?
Mutation
4
2006
2612
0.120
Why?
Gene Editing
1
2020
321
0.120
Why?
Gene Expression Regulation, Developmental
1
2019
642
0.120
Why?
Organ Specificity
1
2016
195
0.120
Why?
Inflammation
2
2019
1147
0.120
Why?
Cytoskeleton
2
2006
139
0.110
Why?
Sterol Regulatory Element Binding Protein 1
2
2011
22
0.110
Why?
Up-Regulation
2
2006
374
0.110
Why?
Epithelial Cells
2
2025
390
0.110
Why?
Bone Morphogenetic Protein 7
1
2014
16
0.110
Why?
MyoD Protein
1
2014
45
0.110
Why?
Receptor, Insulin
1
2014
50
0.110
Why?
Diet
1
2017
527
0.110
Why?
Stem Cells
1
2016
259
0.110
Why?
Cell Proliferation
3
2013
988
0.100
Why?
Th2 Cells
1
2013
98
0.100
Why?
Proto-Oncogene Proteins
2
2005
325
0.100
Why?
Receptors, Cell Surface
1
2015
429
0.100
Why?
Receptors, Adrenergic, beta-3
1
2012
6
0.100
Why?
Lipomatosis
1
2012
8
0.100
Why?
Histological Techniques
1
2012
18
0.100
Why?
Leukemia
1
2012
62
0.090
Why?
Hematopoiesis
1
2012
124
0.090
Why?
Muscle Cells
1
2011
28
0.090
Why?
Real-Time Polymerase Chain Reaction
1
2012
207
0.090
Why?
Sterol Regulatory Element Binding Protein 2
1
2011
6
0.090
Why?
Sarcoma
1
2011
36
0.090
Why?
Cell Separation
1
2011
147
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2012
542
0.090
Why?
Ribosomal Protein S6
1
2011
1
0.090
Why?
Lymphocyte Activation
1
2013
758
0.090
Why?
Longevity
1
2012
113
0.090
Why?
Drug Discovery
1
2012
95
0.090
Why?
Membrane Proteins
1
2017
895
0.090
Why?
Antineoplastic Agents
2
2024
663
0.080
Why?
Adenosine Triphosphate
1
2012
293
0.080
Why?
Regulatory-Associated Protein of mTOR
4
2013
7
0.080
Why?
Tacrolimus Binding Protein 1A
1
2009
2
0.080
Why?
Cell Line
3
2015
2040
0.080
Why?
Everolimus
1
2009
22
0.080
Why?
Microarray Analysis
2
2011
65
0.080
Why?
Green Fluorescent Proteins
2
2001
367
0.080
Why?
Mice, Obese
2
2019
80
0.080
Why?
T-Lymphocytes
1
2013
1007
0.070
Why?
Neoplasm Transplantation
1
2009
167
0.070
Why?
Fluorescent Antibody Technique
3
2011
234
0.070
Why?
Recombinant Proteins
1
2011
702
0.070
Why?
Mice, Nude
1
2009
277
0.070
Why?
Transplantation, Heterologous
1
2009
229
0.070
Why?
Prostate
1
2009
90
0.070
Why?
Phenotype
2
2009
1207
0.070
Why?
Drosophila melanogaster
3
2011
489
0.070
Why?
3T3 Cells
2
2018
110
0.070
Why?
Aged, 80 and over
1
2017
5463
0.070
Why?
Young Adult
1
2017
4695
0.070
Why?
Mice, Inbred BALB C
1
2009
883
0.070
Why?
Forkhead Box Protein O3
1
2006
9
0.070
Why?
Fetal Viability
1
2006
4
0.070
Why?
Fibroblasts
1
2009
394
0.070
Why?
Immunosuppressive Agents
1
2009
378
0.070
Why?
Fetal Development
1
2006
16
0.070
Why?
Glycogen Synthase Kinase 3 beta
1
2006
32
0.060
Why?
Glycogen Synthase Kinase 3
1
2006
45
0.060
Why?
Bacterial Proteins
1
2012
768
0.060
Why?
Cell Enlargement
1
2006
9
0.060
Why?
Middle Aged
3
2019
17615
0.060
Why?
Embryo, Mammalian
1
2006
157
0.060
Why?
Precipitin Tests
2
2004
77
0.060
Why?
Genes, Tumor Suppressor
1
2005
72
0.060
Why?
Oxidative Phosphorylation
1
2025
41
0.060
Why?
Down-Regulation
1
2006
319
0.060
Why?
DNA Copy Number Variations
1
2025
71
0.060
Why?
Electrophoresis, Polyacrylamide Gel
2
2004
182
0.060
Why?
Mammary Glands, Human
1
2025
56
0.060
Why?
Immunoblotting
2
2004
204
0.060
Why?
Blotting, Western
2
2011
612
0.060
Why?
Cell Cycle
3
2013
392
0.060
Why?
Pyrimidines
1
2025
137
0.060
Why?
Transcription, Genetic
2
2015
878
0.050
Why?
Amino Acid Sequence
3
2004
1592
0.050
Why?
Ribosomes
1
2006
163
0.050
Why?
Molecular Sequence Data
3
2004
1991
0.050
Why?
Cell Line, Tumor
2
2024
1470
0.050
Why?
Adrenergic Agents
1
2022
15
0.050
Why?
Phosphoproteins
1
2004
220
0.050
Why?
Cell Death
1
2024
284
0.050
Why?
Plant Cells
1
2002
11
0.050
Why?
Actomyosin
1
2002
21
0.050
Why?
Yeasts
1
2002
49
0.050
Why?
Microtubule-Associated Proteins
1
2002
115
0.050
Why?
Cyclin-Dependent Kinases
1
2002
46
0.050
Why?
Carbon Isotopes
1
2022
17
0.050
Why?
Eukaryotic Cells
1
2002
57
0.050
Why?
Tumor Suppressor Protein p53
1
2024
309
0.050
Why?
Aged
1
2017
14449
0.050
Why?
Phosphotransferases
1
2001
23
0.040
Why?
Microtubules
1
2002
209
0.040
Why?
RNA
1
2004
423
0.040
Why?
Catalysis
1
2001
161
0.040
Why?
Plasmids
1
2001
292
0.040
Why?
Catalytic Domain
1
2001
199
0.040
Why?
Mass Spectrometry
1
2022
301
0.040
Why?
Structure-Activity Relationship
1
2001
373
0.040
Why?
Gene Ontology
1
2020
38
0.040
Why?
Temperature
1
2001
307
0.040
Why?
Tubulin
1
2000
73
0.040
Why?
Chromatography, Liquid
1
2020
131
0.040
Why?
Alleles
1
2001
448
0.040
Why?
Mutagenesis
1
2000
133
0.040
Why?
Microscopy, Fluorescence
1
2001
401
0.040
Why?
Recombinant Fusion Proteins
1
2001
489
0.040
Why?
Neural Tube
1
2019
12
0.040
Why?
Sequence Homology, Amino Acid
1
2000
363
0.040
Why?
Twist-Related Protein 1
1
2019
11
0.040
Why?
Cloning, Molecular
1
2000
383
0.040
Why?
Tandem Mass Spectrometry
1
2020
147
0.040
Why?
Acetylation
1
2019
120
0.040
Why?
Carnitine O-Acetyltransferase
1
2018
1
0.040
Why?
Neuroglia
1
2019
79
0.040
Why?
Mice, Mutant Strains
1
2019
302
0.040
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2019
126
0.040
Why?
Protein Biosynthesis
1
2001
320
0.040
Why?
Apoptosis
1
2024
1079
0.040
Why?
Lentivirus
1
2018
66
0.040
Why?
Single-Cell Analysis
1
2019
114
0.040
Why?
DNA-Binding Proteins
1
2004
1186
0.030
Why?
Cytosol
1
2018
180
0.030
Why?
Hypoxia
1
2018
115
0.030
Why?
RNA, Small Interfering
2
2018
921
0.030
Why?
Ubiquitin-Conjugating Enzymes
1
2016
24
0.030
Why?
3T3-L1 Cells
1
2017
90
0.030
Why?
NIH 3T3 Cells
1
2017
99
0.030
Why?
Nerve Tissue Proteins
1
2019
424
0.030
Why?
Mitochondria
1
2020
371
0.030
Why?
Bone Morphogenetic Proteins
1
2017
62
0.030
Why?
Ubiquitination
1
2016
111
0.030
Why?
Breast Neoplasms
1
2025
1198
0.030
Why?
Gene Knockdown Techniques
1
2017
202
0.030
Why?
Neovascularization, Physiologic
1
2017
104
0.030
Why?
CCAAT-Enhancer-Binding Protein-alpha
1
2015
14
0.030
Why?
CCAAT-Enhancer-Binding Protein-beta
1
2015
21
0.030
Why?
RNA Polymerase II
1
2015
84
0.030
Why?
Mycobacterium tuberculosis
1
2019
405
0.030
Why?
CRISPR-Cas Systems
1
2018
361
0.030
Why?
Enzyme Activation
2
2005
381
0.030
Why?
Sequence Alignment
2
2004
299
0.030
Why?
Neurons
1
2019
922
0.030
Why?
Hematopoietic Stem Cell Mobilization
1
2012
15
0.020
Why?
Gene Expression Regulation, Leukemic
1
2012
51
0.020
Why?
Time Factors
1
2000
3768
0.020
Why?
Gluconeogenesis
1
2012
15
0.020
Why?
Glucose Clamp Technique
1
2012
57
0.020
Why?
Muscle Neoplasms
1
2011
9
0.020
Why?
Aurothioglucose
1
2011
2
0.020
Why?
Hepatocyte Nuclear Factor 3-beta
1
2011
5
0.020
Why?
Phosphatidate Phosphatase
1
2011
1
0.020
Why?
ras Proteins
1
2011
77
0.020
Why?
Biomarkers
1
2017
1408
0.020
Why?
Survival Analysis
1
2012
583
0.020
Why?
Muscle Fibers, Skeletal
1
2011
94
0.020
Why?
Hematopoietic Stem Cells
1
2012
284
0.020
Why?
Chromatin
1
2015
608
0.020
Why?
Molecular Targeted Therapy
1
2011
130
0.020
Why?
Triglycerides
1
2011
244
0.020
Why?
Cytokines
1
2013
935
0.020
Why?
Immunohistochemistry
1
2011
896
0.020
Why?
Gene Regulatory Networks
1
2011
158
0.020
Why?
Hematopoietic Stem Cell Transplantation
1
2012
352
0.020
Why?
Antirheumatic Agents
1
2011
221
0.020
Why?
Gene Expression Regulation, Neoplastic
1
2011
525
0.020
Why?
Genome
1
2011
276
0.020
Why?
Biomarkers, Tumor
1
2011
507
0.020
Why?
Rats
1
2011
1980
0.020
Why?
Models, Genetic
1
2006
260
0.010
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2005
5
0.010
Why?
Immunoprecipitation
1
2005
127
0.010
Why?
Gene Components
1
2004
5
0.010
Why?
Serine
1
2005
91
0.010
Why?
Dose-Response Relationship, Drug
1
2006
864
0.010
Why?
Equipment Failure Analysis
1
2004
75
0.010
Why?
Conserved Sequence
1
2004
173
0.010
Why?
Protein Kinase C
1
2004
102
0.010
Why?
DNA Primers
1
2004
293
0.010
Why?
Macromolecular Substances
1
2004
160
0.010
Why?
Hydrophobic and Hydrophilic Interactions
1
2005
265
0.010
Why?
Genetic Testing
1
2004
134
0.010
Why?
Equipment Design
1
2004
352
0.010
Why?
Software
1
2006
389
0.010
Why?
Actins
1
2004
259
0.010
Why?
Image Processing, Computer-Assisted
1
2006
658
0.010
Why?
Sequence Analysis, DNA
1
2004
415
0.010
Why?
Transfection
1
2004
694
0.010
Why?
Reproducibility of Results
1
2006
1654
0.010
Why?
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